Protein Alignment Cyp4e3 and cyp4v2.2

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001072667.1
• Gene: cyp4v2.2 / 780124
• XenbaseID: XB-GENE-977085
• Length: 523
• Species: Xenopus tropicalis
• Alignment Length: 536
• Identity: 198/536 - (36%)
• Similarity: 291/536 - (54%)
• Gaps: 48/536 - (8%)

  Fly     3 LAVLALLVLPLITLVYFERKASQRRQLLKEFNGPTP-VPILGNANRIGKNPAEILSTFFDWWYDY 66
            |.:|||.:||  .|..:.||    |::||...||.| .|::|:|..:..|..:......::...|
 Frog    20 LTLLALSILP--ALQDYVRK----RRILKPIPGPGPNYPLIGDALFLKNNGGDFFLQICEYTESY 78

  Fly    67 GKDNFL-FWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHKHRKM 130
            .....| .|||....||:.:...:|.:|:|.:.:.|:.:|..||||||.|||||.|.||...|||
 Frog    79 RLQPLLKVWIGTIPFIVVYHADTVEPVLSSSKHMDKAFLYKFLHPWLGKGLLTSTGEKWRSRRKM 143

  Fly   131 ITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPINAME 195
            |||:|||.||.:|.|||||.|...:.:|:....|::...|.: .....||:|.:||||..|.|..
 Frog   144 ITPTFHFAILSEFLEVMNEQSKILVEKLQTHVDGESFDCFMD-VTLCALDIISETAMGRKIQAQS 207

  Fly   196 QRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQDFTYDIIEKRVYALQN 260
            .|||..|||...|...|..|...|:...:.:::...:...:.|.||.|..||...|.:|...|:.
 Frog   208 NRDSEYVQAIYKMSDIIQRRQKMPWLWLDFLYAHLRDGKEHDKNLKILHSFTDKAILERAEELKK 272

  Fly   261 -GGSKEDH---DP--SLPRKKMAFLDTLLSSTID-GRPLTRQEIYEEVSTFMFEGHDTTTSGVSF 318
             |..|::|   ||  ..|:|:.||||.||.:|.| |..::..:|.|||.||||||||||.:.:::
 Frog   273 MGEQKKEHCDSDPESDKPKKRSAFLDMLLMATDDAGNKMSYMDIREEVDTFMFEGHDTTAAALNW 337

  Fly   319 SVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDK 383
            |::||..||:.||::::|..||.|.. :|.|:..::.|::||:..|||:.|:|||||..||...:
 Frog   338 SLFLLGSHPEAQRQVHKELDEVFGKS-DRPVTMDDLKKLRYLEAVIKESLRIYPSVPLFGRTVTE 401

  Fly   384 DYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKPA---PFEYLPFSAGPRNCIG 445
            |..|.|..||||..:.:....|..:...|.:|..||||||..|..:   |:.|:|||||.|||||
 Frog   402 DCSIRGFHVPKGVNVVIIPYALHRDPEYFPEPEEFRPERFFPENASGRNPYAYIPFSAGLRNCIG 466

  Fly   446 QKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKYDPILSAVLT 510
            |:|||:|.|.|:|.::|::.|                            ||.:.:.:..|...|.
 Frog   467 QRFALMEEKVVLSSILRNYWV----------------------------EASQKREELCLLGELI 503

  Fly   511 LKSDNGLHLRLRERRS 526
            |:..:|:.::|:.|.:
 Frog   504 LRPQDGMWIKLKNRET 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	176/461 (38%)
cyp4v2.2	NP_001072667.1	CYP4V	70..512	CDD:410773	177/471 (38%)