Protein Alignment Cyp4e3 and Cyp4f37

DIOPT Version :9

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001093657.1
• Gene: Cyp4f37 / 677156
• MGIID: 3780112
• Length: 546
• Species: Mus musculus
• Alignment Length: 475
• Identity: 135/475 - (28%)
• Similarity: 243/475 - (51%)
• Gaps: 64/475 - (13%)

  Fly    68 KDNFLFWIGYSSHIV-MTNPKQLEYILNSQQLI--QKSTIYDLLHPWLGHGLLTSFGSKWHKHRK 129
            :|..|.|:|....:: :.:|..:..:|.:..|:  :.:|.:..:.||||.||..:.|.||.:||:
Mouse    85 RDVHLCWLGPVIPVLRIVDPAFVAPLLLASALVAPKDTTFHTFVKPWLGDGLFLNSGDKWSRHRR 149

  Fly   130 MITPSFHFNILQDFHEVMNENSAKFMTQLKK--ASAGDTIIDFQEHANYLTLDVICDTAMGVPIN 192
            ::||:|||:||:.:.::.|: |...|....|  :|.|...::..||.:.:|||.:.....|...|
Mouse   150 LLTPAFHFDILKPYVKIFNQ-SVNIMHAKWKHLSSEGSARLEMFEHISLMTLDSLQKCLFGFDSN 213

  Fly   193 AMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSL-------TPEFSAYQKTLKTLQDFTYDI 250
            ..|. .|..:.|..::...:       .|||:::|..       |.:...::|....:.:||..:
Mouse   214 CQES-PSEYISAILELSSLV-------IKRSHQLFLFVDFLYYHTADGRRFRKACDLVHNFTDAV 270

  Fly   251 IEKRVYALQNGGSKEDHDPSL----PRKKMAFLDTLLSSTID-GRPLTRQEIYEEVSTFMFEGHD 310
            |.:|.:.|    |.::||..|    ..|.:.|:|.||.:..: |:.|:.::|..|..||||.|||
Mouse   271 IRERRHTL----SSQNHDEFLKSKTKSKTLDFIDVLLLAKDEHGKELSDEDIRAEADTFMFGGHD 331

  Fly   311 TTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVP 375
            ||.|.:|:.:|.|:|||:.|.:..:|..|::.....:.:.:.::|::.:|.:.|||:.|::|.|.
Mouse   332 TTASALSWILYNLARHPEYQERCRQEVQELLRGREPQEIEWDDLAQLPFLTMCIKESLRLHPPVI 396

  Fly   376 FIGRYCDKDYDI-NGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEE---KPAPFEYLPF 436
            .:.|.|.:|..: :|.::|||....:::..:.:|..::.||..:.|.||:.|   |..|..::||
Mouse   397 DLLRRCTRDIVLPDGRVIPKGNICVISIFGIHHNPSVWPDPEVYDPFRFDPENAHKRPPLAFIPF 461

  Fly   437 SAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKY 501
            ||||||||||.||:.|:...::..:..|.:|                    ||:|
Mouse   462 SAGPRNCIGQTFAMNEMMVALALTLLRFRIL--------------------PDDK---------- 496

  Fly   502 DPILSAVLTLKSDNGLHLRL 521
            :|.....:.|:::.||.||:
Mouse   497 EPRRKPEIILRAEGGLWLRV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	125/420 (30%)
Cyp4f37	NP_001093657.1	CYP4F	74..515	CDD:410772	133/472 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845164
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.640