Protein Alignment Cyp4e3 and Cyp4a31

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_964002.2
• Gene: Cyp4a31 / 666168
• MGIID: 3028580
• Length: 509
• Species: Mus musculus
• Alignment Length: 543
• Identity: 146/543 - (26%)
• Similarity: 260/543 - (47%)
• Gaps: 90/543 - (16%)

  Fly     8 LLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFDWWYDYGK---- 68
            ||:|.....||..||  ...:.|::|..|.                      |.|::.:.:
Mouse    28 LLLLVKAVQVYLHRK--WLLKALQQFPSPP----------------------FHWFFGHEQFKGD 68

  Fly    69 ----------DNF------LFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLL 117
                      :||      .|| |..:::.:.:|..::.||.... .:.:..|.||.||:|:|||
Mouse    69 QELQEIVSCIENFPSAFPRWFW-GSKAYLTVYDPDYMKVILGRSD-PKANGAYRLLAPWIGYGLL 131

  Fly   118 TSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVI 182
            ...|..|.:||||:||:||::||:.:.:.|.::....:.:.::.:..|:.|:..:|.:.:|||.:
Mouse   132 LLNGQSWFQHRKMLTPAFHYDILKTYVKNMADSIRLMLDKWERLAGQDSSIEIFQHISLMTLDTV 196

  Fly   183 CDTAM----GVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTL 243
            ...|.    .|.::.   ...:.:||..|:...::.|..:.|.:::.::.|:.......:..:..
Mouse   197 MKCAFSHKGSVQVDG---NYKTYLQAIGDLNNLVHSRVRNMFHQNDTIYKLSSNGRLSNQACQLA 258

  Fly   244 QDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDGR-PLTRQEIYEEVSTFMFE 307
            .|.|..:|:.|...||:.|..|:   ...::::.|||.||.:.::.. .::.:::..||.|||.|
Mouse   259 HDHTDGVIKMRKDQLQDEGELEN---IKKKRRLDFLDILLFARMENEDSMSDKDLRAEVDTFMIE 320

  Fly   308 GHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYP 372
            |||||.||||:..|.|:.||:.|::...|...::|.  ..|:::..:.::.|..:.||||.|:||
Mouse   321 GHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGD--GSSITWDHLDQIPYTTMCIKEALRLYP 383

  Fly   373 SVPFIGRYCDKDYDI-NGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKPA-PFEYLP 435
            .||.|||........ :|..:|||..:.|::..|.:|.:::.:|..|.|.||..:.|. ...:||
Mouse   384 PVPSIGRELSTSVTFPDGCSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSHSFLP 448

  Fly   436 FSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHK 500
            ||.|.|||||::||:.|||.:::..:..||:||....:
Mouse   449 FSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRV--------------------------- 486

  Fly   501 YDPILSAVLTLKSDNGLHLRLRE 523
              |:..|...|||.||::|.|::
Mouse   487 --PMSLARFVLKSKNGIYLHLKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	132/477 (28%)
Cyp4a31	NP_964002.2	CYP4B-like	71..504	CDD:410771	132/471 (28%)