Protein Alignment Cyp4e3 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 560
• Identity: 149/560 - (26%)
• Similarity: 245/560 - (43%)
• Gaps: 106/560 - (18%)

  Fly     2 WLAVLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVP----ILGNAN---RIGKNPAEILSTF 59
            |.|:| ||.|.||..:.|...............||   |    .||::.   |:.||...:...|
 Frog     9 WAALL-LLALILICFLLFSGYIHYIHMKYDHIPGP---PRDSFFLGHSPTMLRLMKNNLLMYDHF 69

  Fly    60 FDWWYDYG---KDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLH-----PWLGHGL 116
            ..|...||   :.|.|    :...|::.:|:.::.:|.|.: ..|...||::.     .::|.||
 Frog    70 LGWVQKYGPVVRINGL----HRVIILVVSPEAVKELLMSPK-YSKDKFYDVIANMFGVRFMGKGL 129

  Fly   117 LTSFG-SKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLD 180
            :|... ..|||.|:::.|:|....|.......||.:.:.|.:|.:.:.|...|...:..:.||||
 Frog   130 VTDRDYDHWHKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLMEKADGKCEIKMHDMLSRLTLD 194

  Fly   181 VICDTAMGVPINAMEQRDSSIVQAFRDMCYNI-NMRAFHPFKRSNRVFSLTPE--FSAYQKTLKT 242
            ||...|.|:.:|::....:...:|...:...| .||  :|..|    :||...  ....|::::.
 Frog   195 VIGKVAFGMELNSLNDDLTPFPKAISLVMKGIVEMR--NPMVR----YSLAKRGFIRKVQESIRL 253

  Fly   243 LQDFTYDIIEKRVYALQNG---------------GSKEDHDPSLPRKKMAFLDTLLSSTIDGRPL 292
            |:....:.||:|...:|:|               ..:|:.||.:      .||..:
 Frog   254 LRQTGKECIERRQKQIQDGEEIPVDILTQILKGAAMEEECDPEI------LLDNFV--------- 303

  Fly   293 TRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKM 357
                      ||...|.:||.:.:||.|..|.|:|::..|...|..||:|  ..|.:.::::.|:
 Frog   304 ----------TFFIAGQETTANQLSFVVMELGRNPEILEKAQAEIDEVIG--SKRDIEYEDLGKL 356

  Fly   358 KYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPER 422
            :||...:||..|:||:.|...|...:|..|:|..||:..|:.|...::|..::.:.||..|.|:|
 Frog   357 QYLSQVLKETLRLYPTAPGTSRGLTEDMVIDGVKVPENVTIMLNSYIMGRMEQYYSDPLTFNPDR 421

  Fly   423 FEEEKPAP-FEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGL 486
            |..:.|.| :.|.|||.|||:||||.|:.:|.|.|::|:::.:|                  ..|
 Frog   422 FSPDAPKPYYSYFPFSLGPRSCIGQVFSQMEAKVVMAKLLQRYE------------------FEL 468

  Fly   487 APDEKLKREAGRHKYDPILSAVLTLKSDNGLHLRLRERRS 526
            |..:..|          ||... ||:..:|:..|||.|.|
 Frog   469 AEGQSFK----------ILDTG-TLRPLDGVICRLRPRTS 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	127/467 (27%)
cyp46a1.3	NP_001027517.1	p450	40..491	CDD:306555	135/520 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910