Protein Alignment Cyp4e3 and CYP4F11

DIOPT Version :9

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001122404.1
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 482
• Identity: 144/482 - (29%)
• Similarity: 247/482 - (51%)
• Gaps: 50/482 - (10%)

  Fly    50 KNPAEILSTFFDWWYDYGKDNFLFWIGYS-SHIVMTNPKQLEYILNSQQLI--QKSTIYDLLHPW 111
            |...::::|:        ...|..|:|.: ..:::.:|..:..|.::...:  :....|..|.||
Human    75 KTLTQLVTTY--------PQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPW 131

  Fly   112 LGHGLLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQ--LKKASAGDTIIDFQEHA 174
            ||.|||.|.|.||.:||:|:||:||||||:.:.::.|: |...|..  .:.||.|...:|..||.
Human   132 LGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNK-SVNIMHDKWQRLASEGSARLDMFEHI 195

  Fly   175 NYLTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKT 239
            :.:|||.:.........|..| :.|..:.|..::...:..|.......::.::.|||:...:::.
Human   196 SLMTLDSLQKCVFSFESNCQE-KPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRA 259

  Fly   240 LKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDT-LLSSTIDGRPLTRQEIYEEVST 303
            ...:.|||..:|::|...|...|..:........|.:.|:|. |||...||:.|:.::|..|..|
Human   260 CHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADT 324

  Fly   304 FMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQ 368
            |||||||||.||:|:.:|.|::||:.|.:..:|..|::.......:.:.::|::.:|.:.|||:.
Human   325 FMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESL 389

  Fly   369 RVYPSVPFIGRYCDKDYDI-NGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEE---KPA 429
            |::|.||.|.|.|.:|:.: :|.::|||....:.:|.:.||..::.||..:.|.||::|   :.:
Human   390 RLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQENIKERS 454

  Fly   430 PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKR 494
            |..::||||||||||||.||:.|:|.|::..:..|.:||...|
Human   455 PLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTE---------------------- 497

  Fly   495 EAGRHKYDPILSAVLTLKSDNGLHLRL 521
                    |.....|.|:::.||.||:
Human   498 --------PRRKPELILRAEGGLWLRV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	134/427 (31%)
CYP4F11	NP_001122404.1	p450	52..506	CDD:365848	139/470 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154761
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.650