Protein Alignment Cyp4e3 and LOC5668322

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_001237903.2
• Gene: LOC5668322 / 5668322
• VectorBaseID: AGAMI1_011677
• Length: 525
• Species: Anopheles gambiae
• Alignment Length: 533
• Identity: 138/533 - (25%)
• Similarity: 226/533 - (42%)
• Gaps: 83/533 - (15%)

  Fly     1 MWLAVLALLVLPLITL---VYFERKASQRRQLLKEFNGPTPVP--ILGNANRIGK--NPAEILST 58
            ||...:.:||..|..|   |||   ..:::...||...|.|.|  ..|:....|.  :..|.|..
Mosquito    23 MWFPTIEILVALLALLGGAVYF---IVRKQSYWKERGVPHPKPTFFFGSFKDAGTKIHFTEELER 84

  Fly    59 FFDWWYDYGKDNFLFWIGYSSHIVMTNPKQLE-----YILNSQQLIQKSTIYDLLHPWLGHGLLT 118
            ::..:  .||..|:.....::.:|:  |..||     ::.:.|....:.|.|:..|..|...|..
Mosquito    85 YYALY--KGKHPFMGVYLLTTPVVL--PLDLELIKAIFVKDFQYFHDRGTYYNEKHDPLTAHLFN 145

  Fly   119 SFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKK-ASAGDTIIDF-----QEHANY- 176
            ..|.||...|..:||:|              .|.|....... .:||..:.||     |:|...
Mosquito   146 LEGQKWRNLRNKMTPTF--------------TSGKMKMMFPTVVAAGQQLRDFMEENVQKHGEME 196

  Fly   177 -------LTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFS 234
                   .|.|||...|.|:..|:|...|:.    ||.|......|  .|.:..|.:...:|:.|
Mosquito   197 LKDVMARFTTDVIGTCAFGIECNSMRDPDAE----FRAMGKLFMDR--QPSQFVNMMVQFSPKLS 255

  Fly   235 ---AYQKTLKTLQDFTYDIIEKRV-YALQNGGSKEDHDPSLPRKKMAFLDTLLSSTID----GRP 291
               ..:...|.:..|...::...: |.::||..:.|           |:|.::....|    ...
Mosquito   256 RLLGIRLIDKEVSTFFLKVVRDTIDYRVKNGIQRND-----------FMDLMIRMLRDTENPEEA 309

  Fly   292 LTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQC--EVMGHDMNRSVSFQEI 354
            ||..|:..:...|.|.|.:|:::.:::::|.|:.:|:||.|  ..||  ||:... |..:::..|
Mosquito   310 LTFNEVAAQAFVFFFAGFETSSTLLTWTLYELALNPEVQEK--GRQCVQEVLAKH-NGEMTYDAI 371

  Fly   355 AKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDI--NGSIVPKGTTLNLALILLGYNDRIFKDPHH 417
            ..|||||..:||:.|.||.||...|...:||.:  ..|::..||.|.:.:..:..:..:|.:|..
Mosquito   372 HDMKYLDQILKESLRKYPPVPMHFRMTAQDYRVPDTDSVIEAGTMLLIPIFSIQRDASLFPEPEK 436

  Fly   418 FRPERF---EEEKPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGR 479
            |.||||   ||.|..||.:.||..|||.|||.:|.:::.:..::.:::.|...|.....:.....
Mosquito   437 FDPERFSAEEEAKRHPFAWTPFGEGPRVCIGLRFGMMQARIGLAYLLQGFSFAPYEKTSIPMKFI 501

  Fly   480 LNTYLGLAPDEKL 492
            .|::: |.|.|.|
Mosquito   502 TNSFI-LGPREGL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	119/459 (26%)
LOC5668322	XP_001237903.2	None