Protein Alignment Cyp4e3 and Cyp4f1

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_062569.2
• Gene: Cyp4f1 / 56266
• RGDID: 70926
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 544
• Identity: 154/544 - (28%)
• Similarity: 270/544 - (49%)
• Gaps: 70/544 - (12%)

  Fly     2 WLAVL----ALLVLPLITLVYFERKASQRRQLLKEFNGPTPVP---ILGNANRIGKNPAE----- 54
            |..:|    :.::..::|.:|...:..:|   |:.|  |.|..   ::|:...:  .|.|
  Rat    19 WQTLLLFGASWILAQILTQIYAAYRNFRR---LRGF--PQPPKRNWLMGHVGMV--TPTEQGLKE 76

  Fly    55 ---ILSTFFDWWYDYGKDNFLFWIGYSSHIV-MTNPKQLEYILNSQQLIQKSTI--YDLLHPWLG 113
               ::.|:        ...||.|||....:: :.:...:..|||:...:....:  |.:|.||||
  Rat    77 LTRLVGTY--------PQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYTILKPWLG 133

  Fly   114 HGLLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKK-ASAGDTIIDFQEHANYL 177
            .|||.|.|.||.:||:|:||:||||||:.:.::.|:::.....:.|: .|.|.:.:|..||.:.:
  Rat   134 DGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWKRLISEGSSRLDMFEHVSLM 198

  Fly   178 TLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKT 242
            |||.:.........|..| :.|..:.|..::...:..|...|....:.:::|||:...:.|....
  Rat   199 TLDSLQKCVFSFDSNCQE-KSSEYIAAILELSALVAKRHQQPLLFMDLLYNLTPDGMRFHKACNL 262

  Fly   243 LQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDT-LLSSTIDGRPLTRQEIYEEVSTFMF 306
            :.:||..:|.:|...|.:.|..|........|.:.|:|. ||:...||:.|:.::|..|..||||
  Rat   263 VHEFTDAVIRERRRTLPDQGLDEFLKSKAKSKTLDFIDVLLLTKDEDGKELSDEDIRAEADTFMF 327

  Fly   307 EGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVY 371
            ||||||.||:|:.:|.|::||:.|.:..:|..|::.......:.:.::|::.:|.:.|||:.|::
  Rat   328 EGHDTTASGLSWILYNLAKHPEYQERCRQEVQELLRDRDPEEIEWDDLAQLPFLTMCIKESLRLH 392

  Fly   372 PSVPFIGRYCDKDYDI-NGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEK---PAPFE 432
            |.|..|.|.|.:|..: :|..:|||....:::..:.:|..::.||..:.|.||:.|.   .:|..
  Rat   393 PPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVWPDPEVYNPFRFDPENIKDSSPLA 457

  Fly   433 YLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAG 497
            ::||||||||||||.||:.|:|..::..:..|.:|                    ||:|
  Rat   458 FIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLL--------------------PDDK------ 496

  Fly   498 RHKYDPILSAVLTLKSDNGLHLRL 521
                :|.....|.|:::.||.||:
  Rat   497 ----EPRRQPELILRAEGGLWLRV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	139/459 (30%)
Cyp4f1	NP_062569.2	CYP4F	74..515	CDD:410772	140/479 (29%)