Protein Alignment Cyp4e3 and cyp3c4

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001071016.1
• Gene: cyp3c4 / 558541
• ZFINID: ZDB-GENE-060929-96
• Length: 507
• Species: Danio rerio
• Alignment Length: 498
• Identity: 120/498 - (24%)
• Similarity: 222/498 - (44%)
• Gaps: 64/498 - (12%)

  Fly     2 WLAVLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTF-FDWWYD 65
            :|:|...||:.:|||::.......|..:.....||.|.|.:|......|.    |..| .:....
Zfish     6 FLSVTWTLVVLVITLLFIYGVWPHRFFIKLGIPGPRPWPFVGTLLSYAKG----LCNFDMECAKK 66

  Fly    66 YGKDNFLFWIGYSSHIVMTNPKQLEYI-------LNSQQLIQKSTIYDLLHPWLGHGLLTSFGSK 123
            |||    .|..|...:.:.....||.|       ..|..:.::.....|..|: ..|::.....:
Zfish    67 YGK----VWGIYDGRLPILMVADLEVIKVVLVKECYSNFINRRKRTTGLAGPF-SDGIIMVKDER 126

  Fly   124 WHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMG 188
            |.:.|..::|.|....|::...:...::.:|:..::|... :..:..:|.....:||||..::..
Zfish   127 WKRMRSTLSPYFTSGRLKEIFPIAMTHADRFIKNMQKKDP-EQPVKIKEVVAPYSLDVITSSSFS 190

  Fly   189 VPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTL---------Q 244
            |.|:::...:...|         ||::.|..|...|.:..|...|.:....||.:         .
Zfish   191 VDIDSINNPEDPFV---------INVKKFIQFNMFNPLLLLILLFPSLAIPLKKMGVTLFSKSAM 246

  Fly   245 DFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTI-------------DGRPLTRQE 296
            ||.|.:::|         .|:||:.. ...::.||..:|.:.|             ..:.||..|
Zfish   247 DFFYSVLKK---------IKDDHNKE-SEGRVDFLKLMLQNQIPDDQIQDSDTSEQPAKGLTDHE 301

  Fly   297 IYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLD 361
            |..:...|:..|::||::.::|.:|.|:.:||...||..|..:  ...::..:::..:.:|.||:
Zfish   302 ILSQSLVFILGGYETTSTTLTFLLYNLATNPDCLEKLVEEIDK--NFPLDTPITYDALMRMDYLE 364

  Fly   362 LFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEE 426
            :.|.|:.|:.|:.|.:.|...|...|||..:|:||.:.:...:|.::..|::.|..||||||..|
Zfish   365 MAINESMRLLPTAPRLERSAKKTVVINGLTIPEGTLVGIPTYVLSHDPDIWESPGEFRPERFSPE 429

  Fly   427 KPAPF---EYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEV 466
            ..:.|   .::||..|||||||.::|::.:|..:.|::::|.|
Zfish   430 NKSEFLQYAFIPFGLGPRNCIGMRYAVMIMKLFVVKLLQNFSV 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	102/431 (24%)
cyp3c4	NP_001071016.1	cytochrome_P450	66..497	CDD:477761	104/434 (24%)