Protein Alignment Cyp4e3 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001025122.2
• Gene: cyp26c1 / 554036
• ZFINID: ZDB-GENE-050714-2
• Length: 554
• Species: Danio rerio
• Alignment Length: 630
• Identity: 136/630 - (21%)
• Similarity: 224/630 - (35%)
• Gaps: 218/630 - (34%)

  Fly     5 VLALL-----VLPLITLVYFERKASQRRQLLKEFNG----------PTPV-----PILGNANRIG 49
            |.|||     |||.:.|:...|       ||.||..          |.|.     |::|..
Zfish     9 VSALLSVADAVLPTVLLLAVSR-------LLWEFRWSITRDRTCKLPLPQGSMGWPLVGET---- 62

  Fly    50 KNPAEILSTFFDWWYD-----------YGKDNFLFWIGYSSHIV------MTNPKQLEYILNSQQ 97
                      |.|.:.           :||       .:.:|::      :|..:.:..||..:.
Zfish    63 ----------FHWLFQGSSFHISRREKHGK-------VFKTHLLGKPLIRVTGAENIRKILLGEH 110

  Fly    98 LI------QKSTIYDLLHPWLGHGLLTSFGSKWHKHRKMITPSFHFNILQDF----HEVMNENSA 152
            .:      |.:.|  :|.|   :.|:.|.|....:.||::...|....|:.:    .:|:....|
Zfish   111 TVVCTQWPQSTRI--ILGP---NTLVNSVGDLHKRKRKVLAKVFSRGALEAYLTRLQDVVKSEIA 170

  Fly   153 KFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAF 217
            |:.|:...       ::....|..||..:.....:|:.:.  ||:.:.:.:.|..:
Zfish   171 KWCTETGS-------VEVYTAAKSLTFRIAVRVLLGLHLE--EQQITYLSKTFEQL--------- 217

  Fly   218 HPFKRSNRVFSL---TPEFSAYQKTLKT---LQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKM 276
                 .|.:|||   || .|..:|.::.   |......|||:::                 :|:.
Zfish   218 -----MNNLFSLPIDTP-VSGLRKGIRAREILHSAMEKIIEEKL-----------------KKQQ 259

  Fly   277 A-----FLDTLLSSTIDG-RPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRK--- 332
            |     ..|.:|||..:. ..||.||:.|.....:|..|.||.|..:..:..|.|||||..:
Zfish   260 ASDYCDAFDYMLSSARENDYELTMQELKETAVELIFAAHSTTASASTSLIMQLLRHPDVSERARA 324

  Fly   333 -LYREQCEVMGHDMNRS------------------------------------------------ 348
             |..|.....||...||
Zfish   325 ELESEGLITDGHGHCRSRCNGNAISEEGEAAEKSTSDRRSAINKATYFEAGDKEEGRRSRTHVPY 389

  Fly   349 VSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFK 413
            :|.::::::.|||..:||..|..|.|....|...:.:::||..:|||.::..::.........::
Zfish   390 LSLEKLSQLSYLDCVVKEVLRFLPPVSGGYRTVLQTFELNGYQIPKGWSVMYSIRDTHETAEAYQ 454

  Fly   414 DPHHFRPERF----EEEKPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELV 474
            :|..|.|:||    ||.|...|.|:||..|.|.|||::.||:.|||:      :.|:|...|..:
Zfish   455 NPELFDPDRFCVGREESKSERFSYVPFGGGVRRCIGRELALIVLKTL------AVELLATADCTL 513

  Fly   475 STDGRLNTYLGLAPDEKLKREAGRHKYDPILSAVLTLKSDNGLHL 519
            :|    .||                   |.:..|..:...||||:
Zfish   514 AT----QTY-------------------PRMQTVPIVHPVNGLHV 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	115/534 (22%)
cyp26c1	NP_001025122.2	cytochrome_P450	59..537	CDD:477761	120/573 (21%)