Protein Alignment Cyp4e3 and cyp51a1

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001016194.1
• Gene: cyp51a1 / 548948
• XenbaseID: XB-GENE-985396
• Length: 499
• Species: Xenopus tropicalis
• Alignment Length: 576
• Identity: 122/576 - (21%)
• Similarity: 216/576 - (37%)
• Gaps: 159/576 - (27%)

  Fly     9 LVLP---LITLVYFERKASQRRQLLKEFNGPTP------VPILGNANRIGKNPAEILSTFFDWWY 64
            :::|   |:.|.|..:.|.:..|.....|...|      :|.||:|...||:|...|...:|
 Frog    25 ILIPCTFLLALAYVSKLAFKHLQAEDPGNVKYPPFISSNIPFLGHAIAFGKSPISFLENAYD--- 86

  Fly    65 DYGK--------DNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFG 121
            .||.        ..|.:.:|..:..::.|.|..:  ||::.:
 Frog    87 KYGPVFSFTMVGKTFTYLVGSDAAALLFNSKNED--LNAEDV----------------------- 126

  Fly   122 SKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYL--------- 177
                 :.::.||.|...:..|....:      |:.|.|....|..|..|:.|...:
 Frog   127 -----YSRLTTPVFGKGVAYDVPNPI------FLEQKKMLKTGLNIAHFKTHVQMIEEETQEYFE 180

  Fly   178 -------------TLDVICDTAM----GVPINAMEQRDSSIVQAFRDMCYNINMRA-----FHPF 220
                         ..::|..||.    |..|.:|  .:..:.|.:.|:.......|     :.|.
 Frog   181 RWGDSGVRNLFEALSELIILTASRCLHGKEIRSM--LNERVAQLYADLDGGFTHAAWLLPGWLPL 243

  Fly   221 KRSNRVFSLTPEFSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSS 285
                      |.|....:..:.:::..|.:|:||    :|...:||.          .|.|||.:
 Frog   244 ----------PSFRRRDRAHREIKNIFYQVIQKR----RNSAEREDD----------MLQTLLDA 284

  Fly   286 TI-DGRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSV 349
            |. ||.||...||...:...:..|..|:::..::..:.|:::..:|.:.:.||..|.|.|: ..:
 Frog   285 TYKDGTPLNDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLAKNKSLQAQCFAEQKAVCGEDL-PPL 348

  Fly   350 SFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKG------TTLNLALILLGYN 408
            ::.::..::.||..|||..|:.|.:..:.|.......:.|..:|.|      .|:|..|     .
 Frog   349 NYDQLKDLQALDRCIKETLRLRPPIMTMMRMARTPQSVAGYNIPPGHQVCVSPTVNHRL-----R 408

  Fly   409 DRIFKDPHHFRPERFEEEKPA---PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAV 470
            |...|:. .|.|:|:..:.||   .|.|:||.||...|||:.||.:::||:.|.::|.:|.
 Frog   409 DTWDKNT-DFNPDRYLHDNPAAGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRMYEF---- 468

  Fly   471 DELVSTDGRLNTYLGLAPDEKLKREAGRHKYDPILSAVLTLKSDNGLHLRLRERRS 526
             |||  ||                      |.|.::....:.:.|...:|.:.|::
 Frog   469 -ELV--DG----------------------YFPTINYTTMIHTPNNPVIRYKRRKN 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	101/499 (20%)
cyp51a1	NP_001016194.1	CYP51-like	84..495	CDD:410668	105/511 (21%)