Protein Alignment Cyp4e3 and cyp26a1

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_012822016.1
• Gene: cyp26a1 / 548901
• XenbaseID: XB-GENE-855583
• Length: 492
• Species: Xenopus tropicalis
• Alignment Length: 549
• Identity: 125/549 - (22%)
• Similarity: 219/549 - (39%)
• Gaps: 110/549 - (20%)

  Fly     3 LAVLALLVLPLITL-----VY-FERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFD 61
            |..|||.||.|:|.     || ..||.:..|..|..  |...:|..|...::.....:.|..
 Frog    11 LCTLALPVLLLLTAAKLWEVYCLSRKDASCRNPLPP--GTMGLPFFGETLQMVLQRRKFLQV--- 70

  Fly    62 WWYDYGKDNFLFWIGYSSHIV---------MTNPKQLEYILNSQQLIQKSTIYDLLHPW------ 111
            ....||:.       |.:|:.         ..|.:|:  :|...:|:.       :| |
 Frog    71 KRRKYGRI-------YKTHLFGSPTVRVTGAENVRQI--LLGEHKLVS-------VH-WPASVRT 118

  Fly   112 -LGHGLLTSFGSKWHKH-RKMITPSFHFNILQDFHEVMNENSAKFMTQLKKA----SAGDTIIDF 170
             ||.|.|::.....||: :|:|..:|....|.::..:|.|       :|:::    ...|:.:..
 Frog   119 ILGAGCLSNLHDSEHKYTKKVIMQAFSREALANYVPLMEE-------ELRRSVNLWLQSDSCVLV 176

  Fly   171 QEHANYLTLDVICDTAMGV-PINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPE-- 232
            ......|...:.....:|. |.....:::.::::||.:|..|:              |||..:
 Frog   177 YPAIKRLMFRIAMRLLLGCDPQRLGREQEETLLEAFEEMTRNL--------------FSLPIDVP 227

  Fly   233 FSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTID-----GRPL 292
            ||...:.|:     ..:||..::        :|:....|.|:........|...||     |.|:
 Frog   228 FSGLYRGLR-----ARNIIHAQI--------EENIKEKLQREPDGQCRDALQLLIDHSRRTGEPV 279

  Fly   293 TRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMG-----HDMNRSVSFQ 352
            ..|.:.|..:..:|.||.||.|..:.....|:.|.||..|: |::.|..|     .:..:.:|.:
 Frog   280 NLQALKESATELLFGGHGTTASAATSLTTFLALHKDVLEKV-RKELESQGLLSNKPEEKKELSIE 343

  Fly   353 EIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHH 417
            .:.::||....|||..|:.|.|....|...|.:.:||..:|||..:..::........:|.|...
 Frog   344 VLQQLKYTSCVIKETLRLSPPVAGGFRVALKTFVLNGYQIPKGWNVIYSIADTHGEAELFPDKDE 408

  Fly   418 FRPERFEEEKP---APFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGR 479
            |.|:||....|   :.|.::||..|.|.|:|::||.:.||..|.::.|:.:.     ||::....
 Frog   409 FNPDRFLTPLPGDSSRFGFIPFGGGVRCCVGKEFAKILLKVFIVELCRNCDW-----ELLNGSPA 468

  Fly   480 LNTYLGLAPDEKLKREAGRHKYDPILSAV 508
            :.|...:.|.:.|..     |:.|..|::
 Frog   469 MKTSPIICPVDNLPA-----KFKPFASSI 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	105/478 (22%)
cyp26a1	XP_012822016.1	cytochrome_P450	55..485	CDD:477761	106/494 (21%)