Protein Alignment Cyp4e3 and Cyp2c67

DIOPT Version :9

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001019890.1
• Gene: Cyp2c67 / 545288
• MGIID: 3612288
• Length: 491
• Species: Mus musculus
• Alignment Length: 516
• Identity: 118/516 - (22%)
• Similarity: 209/516 - (40%)
• Gaps: 106/516 - (20%)

  Fly     5 VLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRIG-KNPAEILSTFFDWWYDYGK 68
            |:.:|.|..:.::...|:.|.|..|..   ||||:||:||.:.|. |:..:.|:.|..   .||
Mouse     5 VVLVLCLSFLLVLSLWRQRSARGNLPP---GPTPLPIIGNYHLIDMKDIGQCLTNFSK---TYG- 62

  Fly    69 DNFLFWIGYSSHIVMTNPKQLE--YILNSQQLIQKS--TIYDLLHPWLGHGLLTSFGSKWHKHRK 129
            ..|..:.|....:|:...:.::  :|.:.::...:.  ..:|.:..  |.|:..|.|:.|
Mouse    63 PVFTLYFGSQPIVVLHGYEAMKEAFIDHGEEFSGRGRFPFFDKVTK--GKGIGFSHGNVW----- 120

  Fly   130 MITPSFHFNILQD-------FHEVMNENSAKFMTQLKKASA-------------GDTI--IDFQE 172
            ..|..|..|.|::       ....:.|.:...|.:|||.:.             .:.|  |.||.
Mouse   121 KATRVFTINTLRNLGMGKRTIENKVQEEAQWLMKELKKTNGLPCDPQFIIGCAPCNVICSIVFQN 185

  Fly   173 HANYLTLDVICDTAMGVPINAMEQRDSSIVQAFR------DMCYNINMRAFHPFKRSNRVFSLTP 231
            ..:|...|.:  :.:|......|...|...|.|.      |.|..          |.|:.|....
Mouse   186 RFDYKDKDFL--SLIGKVNECTEILSSPGCQIFNAVPILIDYCPG----------RHNKFFKNHT 238

  Fly   232 EFSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSL----PRKKMAFLDTLL-----SSTI 287
            ...:|             ::||          .::|:.||    ||.   |:|..|     ...|
Mouse   239 WIKSY-------------LLEK----------IKEHEESLDVTNPRD---FIDYFLIQRCQEKGI 277

  Fly   288 DGRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQ 352
            :....|.:.:...|:..:|.|.::.:|.:.|::.||.:|..:..|:..|...|:|.  :||...|
Mouse   278 EHMEYTIEHLATLVTDLVFGGTESLSSTMRFALLLLMKHTHITAKVQEEIDNVIGR--HRSPCMQ 340

  Fly   353 EIAKMKYLDLFIKEAQRVYPSVPFIGRY---CDKDYDINGSIVPKGTTLNLALILLGYNDRIFKD 414
            :...|.|.:..:.|.||.....|....:   ||..:  ....:||||.:..:|..:.::...|.:
Mouse   341 DRNHMPYTNAMVHEVQRYVDLGPISLVHEVTCDTKF--RNYFIPKGTQVMTSLTSVLHDSTEFPN 403

  Fly   415 PHHFRPERFEEE----KPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVD 471
            |..|.|..|.::    |.:.: ::|||||.|.|:|:..|.:||...::.::::|::.|.||
Mouse   404 PEVFDPGHFLDDNGNFKKSDY-FVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVD 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	108/481 (22%)
Cyp2c67	NP_001019890.1	p450	30..487	CDD:278495	111/491 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010