Protein Alignment Cyp4e3 and LOC4577153

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_061508324.1
• Gene: LOC4577153 / 4577153
• VectorBaseID: AGAMI1_013061
• Length: 501
• Species: Anopheles gambiae
• Alignment Length: 542
• Identity: 182/542 - (33%)
• Similarity: 277/542 - (51%)
• Gaps: 63/542 - (11%)

  Fly     2 WLAVLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGN-ANRIGKNPAEILSTFFDWWYD 65
            |..||.::...|..|.:       :.:..:...||...|.:|| .:.:|..|.||......:...
Mosquito     4 WAVVLGVIATLLAALDW-------KYKSYEHLPGPRRWPFIGNVVSFLGAGPVEIFDQLIAFAST 61

  Fly    66 YGK----DNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHK 126
            |||    |.|     |...|:.::|:..|.||.|.....||..||.:..|:|:|||.|...||..
Mosquito    62 YGKVYKLDFF-----YDYTIIYSSPEAAEAILTSPAFTAKSQDYDKVSEWIGNGLLISRDQKWFT 121

  Fly   127 HRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKAS--AGDTIIDFQEHANYLTLDVICDTAMGV 189
            |||:|||.|||.||::|..|.|..:..|..:|:..:  :.|.:..|.| ...|||.:||:|||||
Mosquito   122 HRKVITPGFHFKILENFVPVFNRQAEAFCAKLETLTGRSADAVNVFPE-LKLLTLGIICETAMGV 185

  Fly   190 PINAMEQRDSSIVQAF-----RDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQDFTYD 249
               .|:....|..||:     .::...:..|.|:.|...:.||.||.....:.:.:|....||..
Mosquito   186 ---GMDGEGQSTQQAYYTQIVEELSSILYWRMFNVFVNIDAVFRLTRTSRRFDELVKKSWQFTLG 247

  Fly   250 IIEKR--VYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDGRPLTRQEIYEEVSTFMFEGHDTT 312
            :||:|  :..|:....:.:.:.:..::|.|.|||||.:.|||||||.:||.|||.||.|.|||||
Mosquito   248 MIERRRKMNELEAPVEERNEEETFGKRKRALLDTLLEARIDGRPLTDEEIREEVDTFTFAGHDTT 312

  Fly   313 TSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFI 377
            .|.::|.:|.:::||::|.::|:|....:|.|. ..:|...:..:.|::|.|||:.|::|.||.|
Mosquito   313 ASAMTFILYNVAKHPEIQERVYQEIVNEIGADF-CELSLSALNNLHYMELVIKESLRLFPPVPVI 376

  Fly   378 GRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKPA----PFEYLPFSA 438
            .|...:|.::....:.:||::.:.:..:.::|..|.|...|.|:|||..:.|    |:.|:||||
Mosquito   377 ARIATEDTELLAERITRGTSVAIDIYTMHHSDDYFPDAERFDPDRFEGARDAQTFNPYTYIPFSA 441

  Fly   439 GPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKYDP 503
            |.|||||||||..|||:.:.|:::.|::            ||                ....|.|
Mosquito   442 GSRNCIGQKFAQYELKSTLVKLLQRFQI------------RL----------------ADASYVP 478

  Fly   504 ILSAVLTLKSDNGLHLRLRERR 525
            ||.|.:.||...||.||..:||
Mosquito   479 ILKAEIVLKPAEGLPLRFIKRR 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	162/467 (35%)
LOC4577153	XP_061508324.1	None