Protein Alignment Cyp4e3 and cyp51

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001001730.2
• Gene: cyp51 / 414331
• ZFINID: ZDB-GENE-040625-2
• Length: 499
• Species: Danio rerio
• Alignment Length: 512
• Identity: 112/512 - (21%)
• Similarity: 202/512 - (39%)
• Gaps: 121/512 - (23%)

  Fly    14 ITLVYFER-----KASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFDWWYDYGK----- 68
            :||.||.:     .:|:..:.....  |:.:|.||.|...|::|.|.|...::   .||.
Zfish    32 LTLGYFSKLLFTQHSSEHTKYPPHI--PSSLPFLGQAVAFGRSPIEFLEKAYE---QYGPVVSFT 91

  Fly    69 ---DNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHKHRKM 130
               ..|.:.:|..:..:|.|.|..:  ||::.:                            :.::
Zfish    92 MVGKTFTYLLGSDAAALMFNSKNED--LNAEDV----------------------------YARL 126

  Fly   131 ITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPINAME 195
            .||.|...:..|....:      |:.|.|....|..|..|::|     :::|.:..........|
Zfish   127 TTPVFGKGVAYDVPNPL------FLEQKKMLKTGLNIAQFKQH-----VEIIEEETKDYFRRWGE 180

  Fly   196 QRDSSIVQAFRDMCYNINMRAFHPFK-RS---NRVFSL--------------------TPEFSAY 236
            ..:.::..|..::......|..|..: ||   .||..|                    .|.|...
Zfish   181 SGERNLFDALSELIILTASRCLHGCEIRSLLDERVAQLYADLDGGFTHAAWLLPGWLPLPSFRRR 245

  Fly   237 QKTLKTLQDFTYDIIEKRVYALQNGGSKED---HDPSLPRKKMAFLDTLLSSTI-DGRPLTRQEI 297
            .:....::...|::|:||         :||   ||.        .|.||:.:|. |||||:..||
Zfish   246 DRAHLEIKKIFYNVIKKR---------REDTEKHDD--------ILQTLIDATYKDGRPLSDDEI 293

  Fly   298 YEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDL 362
            ...:...:..|..|:::..::..:.|:|...:|.:.|.||..|.|.:: ..:.:.::..:..||.
Zfish   294 AGMLIGLLLAGQHTSSTTSAWMGFFLARDRALQERCYSEQKSVCGEEL-PPLHYDQLKDLSLLDR 357

  Fly   363 FIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRI---FKDPHHFRPERFE 424
            .:||..|:.|.:..:.|.......:....:|.|..:.::..:   |.|:   :.:...|.|:|:.
Zfish   358 CLKETLRLRPPIMTMMRMAKTPQKVGEYTIPPGHQVCVSPTV---NHRLQDTWAERLDFDPDRYL 419

  Fly   425 EEKPA---PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDG 478
            .:.||   .|.|:||.||...|||:.||.:::||:.|.::|.|:.     |||  ||
Zfish   420 HDNPAAGEKFAYIPFGAGRHRCIGENFAYVQIKTIWSTLLRMFDF-----ELV--DG 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	96/453 (21%)
cyp51	NP_001001730.2	CYP51-like	80..491	CDD:410668	98/462 (21%)