Protein Alignment Cyp4e3 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_956773.1
• Gene: cyp46a1.4 / 393451
• ZFINID: ZDB-GENE-040426-1224
• Length: 444
• Species: Danio rerio
• Alignment Length: 458
• Identity: 131/458 - (28%)
• Similarity: 225/458 - (49%)
• Gaps: 63/458 - (13%)

  Fly    59 FFDWWYDYG---KDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLL-----HPWLGHG 115
            |..|...||   :.|.|.:|.    ||:..|:..:.||.|.:..:...:|..|     ..:||:|
Zfish    12 FLQWAEKYGPVYRINSLHYIA----IVVHCPEATKTILMSPKYTKDPFVYRRLFNLFGKRFLGYG 72

  Fly   116 LLTSFGSK-WHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTL 179
            |:|:.... |::.|:::.|:|..:.|:......:|.|.:.|.:|::.:...|.....:..|.:||
Zfish    73 LITAVDHDIWYRQRRIMDPAFSSSYLRSLISTFDEMSERLMDKLEEMANNKTPAVMHDLVNCVTL 137

  Fly   180 DVICDTAMGVPINAMEQRDSSIVQAFRDMCYN---INMRAFHPFKRSNRVFSLTPEFSAYQKTLK 241
            ||||..|.||.:|.:.|:||....|. ::|.|   :::|  .||      |.|.|:   ..|.:|
Zfish   138 DVICKVAFGVDLNFLTQKDSPFQNAV-ELCLNGMTVDLR--DPF------FRLFPK---NWKLIK 190

  Fly   242 TLQDFTYDI-------IEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSS--------TIDGRP 291
            .::|....:       |:.|..|::||   ||    :|:.   .|..:|.|        |.|
Zfish   191 QIRDAAELLRKTGEKWIQNRKTAVKNG---ED----VPKD---ILTQILKSAEEENVNNTDD--- 242

  Fly   292 LTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAK 356
              .:::.:...||...|.:||.:.:||::..|.|:|::.::...|..||:|  ..|.:|.:::.|
Zfish   243 --LEQMLDNFVTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEVDEVLG--TKREISNEDLGK 303

  Fly   357 MKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPE 421
            ..||...:||..|:||:.|...|:..:|..|:|..:|.|.::..:..:....::.||||..|.||
Zfish   304 FTYLSQVLKETLRLYPTAPGTNRWLHEDMIIDGIKIPGGCSVMFSSYVSQRLEKFFKDPLKFDPE 368

  Fly   422 RFEEEKPAPFE-YLPFSAGPRNCIGQKFALLELKTVISKVVRSFE--VLPAVDELVSTDGRLNTY 483
            ||:...|.|:. |.||:.|||.|:||.|:.:|.|.|::|:::.||  ::|.....:...|.|...
Zfish   369 RFDVNAPKPYYCYFPFALGPRTCLGQVFSQMEAKVVLAKLLQRFEFSLVPGQSFDIKDTGTLRPK 433

  Fly   484 LGL 486
            .|:
Zfish   434 SGV 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	127/446 (28%)
cyp46a1.4	NP_956773.1	CYP46A1-like	9..438	CDD:410706	131/458 (29%)