Protein Alignment Cyp4e3 and Cyp301a1

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Alignment Length: 502
• Identity: 119/502 - (23%)
• Similarity: 213/502 - (42%)
• Gaps: 88/502 - (17%)

  Fly    35 GPTPVPILGNANR----IGK----NPAEILSTFFDWWYDYGK-DNFLFWIGYSSHIVMTNPKQLE 90
            ||.|:|||||..|    ||:    :.|:|.|...|   .||: ..|...||....:.:.:..::|
  Fly    77 GPKPIPILGNTWRLMPIIGQYTISDVAKISSLLHD---RYGRIVRFGGLIGRPDLLFIYDADEIE 138

  Fly    91 YILNSQ----------------QLIQKSTIYDLLHPWLGHGLLTSFGSKWHKHRKMI-TPSFHFN 138
            ....|:                .:::|....||      .|::...|..|.:.|..: .|....:
  Fly   139 KCYRSEGPTPFRPSMPSLVKYKSVVRKDFFGDL------GGVVGVHGEPWREFRSRVQKPVLQLS 197

  Fly   139 ILQDFHEVMNENSAKFMTQLKKASAGDTII--DFQEHANYLTLDVICDTAMGVPINAMEQR---D 198
            .::.:.:.:...:..|:.:.:.....:..:  ||....:..:|:.|...|:...:..:|..   |
  Fly   198 TIRRYLQPLEVITEDFLVRCENLLDENQELPEDFDNEIHKWSLECIGRVALDTRLGCLESNLKPD 262

  Fly   199 S---SIVQAFRDMCYNI---NMRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQDFTYDIIEKRVYA 257
            |   .|:.|.:....|:   .::|  |:.|    :..||.::.|.|.:..........|:.....
  Fly   263 SEPQQIIDAAKYALRNVATLELKA--PYWR----YFPTPLWTRYVKNMNFFVGVCMKYIQSATER 321

  Fly   258 LQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDGRPLTRQEIYEEVSTFM-----FEGHDTTTSGVS 317
            |:.      .||||...:.:.::.::.|..|          |:::|.|     ..|.||.:..|.
  Fly   322 LKT------QDPSLRAGEPSLVEKVILSQKD----------EKIATIMALDLILVGIDTISMAVC 370

  Fly   318 FSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCD 382
            ..:|.|:..|..|:|::.|...:: .|.|..::...:.:|.:|..||||..|:|.:|...||...
  Fly   371 SMLYQLATRPVDQQKVHEELKRLL-PDPNTPLTIPLLDQMHHLKGFIKEVFRMYSTVIGNGRTLM 434

  Fly   383 KDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEE-------KPAPFEYLPFSAGP 440
            :|..|.|..||||.......|:.|..:....|...|||||:.:.       |..||..||:..|.
  Fly   435 EDSVICGYQVPKGVQAVFPTIVTGNMEEYVTDAATFRPERWLKPQHGGTPGKLHPFASLPYGYGA 499

  Fly   441 RNCIGQKFALLELKTVISKVVRSFEV----LP---AVDELVSTDGRL 480
            |.|:|::||.||::.:::|::|::::    .|   ||..:.:.||.|
  Fly   500 RMCLGRRFADLEMQILLAKLLRNYKLEYNHKPLDYAVTFMYAPDGPL 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	102/461 (22%)
Cyp301a1	NP_610796.1	CYP24A1-like	110..547	CDD:410677	105/469 (22%)