Protein Alignment Cyp4e3 and Cyp46a1

DIOPT Version :9

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_006240610.1
• Gene: Cyp46a1 / 362782
• RGDID: 1306605
• Length: 500
• Species: Rattus norvegicus
• Alignment Length: 508
• Identity: 122/508 - (24%)
• Similarity: 227/508 - (44%)
• Gaps: 99/508 - (19%)

  Fly    36 PTPVPILGNANRIGKNPAE----ILSTFFDWWYDYG---KDNFLFWIGYSSHIVMTNPKQLEYIL 93
            |.|..:||:.....|....    :...|.||...||   :.|    :.:.:.:::|:|:.::..|
  Rat    37 PRPSFLLGHLPYFWKKDEACGRVLQDVFLDWAKKYGPVVRVN----VFHKTSVIVTSPESVKKFL 97

  Fly    94 NSQQLIQKSTIYDLLHP-----WLGHGLLT--SFGSKWHKHRKMITPSFHFNILQDFHEVMNENS 151
            .|.:..:.|.:|..:..     ..|.||::  .:| :|:|.|:::..:|..:.|.......||.:
  Rat    98 MSTKYNKDSKMYRAIQTVFGERLFGQGLVSECDYG-RWYKQRRVMDLAFSRSSLVSLMGTFNEKA 161

  Fly   152 AKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNIN--- 213
            .:.|..|:..:.|.|.:..|:.....|:|::...|.|:..:.:......:.||.:.|...|:
  Rat   162 EQLMEILEAKADGQTPVSMQDMLTCATIDILAKAAFGMETSMLLGAQKPLSQAVKVMLEGISASR 226

  Fly   214 --MRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQDFTYDIIEKRVYALQNG--------------- 261
              :..|.|.||.        :....:::::.|:....|.:::|..||:.|
  Rat   227 NTLAKFMPGKRK--------QLREIRESIRLLRQVGKDWVQRRREALKRGEDVPADILTQILKAE 283

  Fly   262 -GSKEDHDPSLPRKKMAFLDTLLSSTIDGRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSR 325
             |:::|             :.||.:.:               ||...||:|:.:.::|:|..|||
  Rat   284 EGAQDD-------------EVLLDNFV---------------TFFIAGHETSANHLAFTVMELSR 320

  Fly   326 HPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGS 390
            .|::..:|..|..||:|  ..|.:.::::.:::||...:||:.|:||......|..:::..|:|.
  Rat   321 QPEIVARLQAEVDEVVG--SKRHLDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGV 383

  Fly   391 IVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKPAP-FEYLPFSAGPRNCIGQKFALLELK 454
            .||..|.|..:..::|..|..|:||..|.|:||....|.| |.|.|||.|.|:||||:||.:|:|
  Rat   384 RVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVK 448

  Fly   455 TVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEK--LKREAGRHKYDPIL 505
            .|::|:::..|                  ..|.|.::  |:.:|.....||:|
  Rat   449 VVMAKLLQRLE------------------FRLVPGQRFGLQEQATLKPLDPVL 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	115/467 (25%)
Cyp46a1	XP_006240610.1	p450	34..466	CDD:278495	117/489 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810