Protein Alignment Cyp4e3 and Cyp28d2

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 548
• Identity: 129/548 - (23%)
• Similarity: 225/548 - (41%)
• Gaps: 148/548 - (27%)

  Fly     8 LLVLPLITLVY--------FERKASQRRQLLKEFNGPTPVPILGNANRI---GKNPAEILSTFFD 61
            :|||.|:.|||        :.||...:       ..|| .|.:|:...|   .:|.|..:...::
  Fly     9 VLVLTLLVLVYVFLTWNFNYWRKRGIK-------TAPT-WPFVGSFPSIFTRKRNIAYDIDDIYE 65

  Fly    62 WWYDYGKDNFLFWIGYSSHIVMTNPKQL-----EYI-----------LNSQ--QLIQKSTIYDLL 108
            .:.|  .||.   :|    :..|...||     |||           .|::  ..:.|.|  |::
  Fly    66 KYKD--TDNM---VG----VFTTRVPQLLVMCPEYIHKIYATDFRSFHNNEWRNFVNKKT--DMI 119

  Fly   109 HPWLGHGLLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKK-----ASAGDTII 168
               ||:......|.:|.:.|..|.|:...|.::..:.|......||:..:::     .|.|   :
  Fly   120 ---LGNNPFVLTGDEWKERRSEIMPALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEG---L 178

  Fly   169 DFQEHANYLTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEF 233
            |..:.:...|.:|:.|..:||.           .|:|.|....:       .|...|||:.:.||
  Fly   179 DAMDLSLCYTTEVVSDCGLGVS-----------AQSFTDTPTPL-------LKMIKRVFNTSFEF 225

  Fly   234 SAY-------QKTL---------KTLQDFTYDIIEKRVYALQNGGSKEDHDP------SLPRKKM 276
            ..|       ||..         |..:.|..||| :|...|:....::..|.      .|..||.
  Fly   226 IFYSVVTNLWQKVRKFYSVPFFNKETEVFFLDII-RRCITLRLEKPEQQRDDFLNYMLQLQEKKG 289

  Fly   277 AFLDTLLSSTIDGRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVM 341
            ...|.:|.:|:               ||:.:|.:||...::..:.:|.|:|:.|.|:.:|    :
  Fly   290 LHTDNILINTM---------------TFILDGFETTALVLAHIMLMLGRNPEEQDKVRKE----I 335

  Fly   342 GHDMNRSVSFQEIAKMKYLDLFIKEAQRVY-PSV--------PFIGRYCDKDYDINGSIV--PKG 395
            |   :..::|.:::::.:||..|.|..|:: |.|        ||  .:.:|    ||..|  ..|
  Fly   336 G---SADLTFDQMSELPHLDACIYETLRLFSPQVAARKLVTEPF--EFANK----NGRTVHLKPG 391

  Fly   396 TTLNLALILLGYNDRIFKDPHHFRPERFEEEKPAPFE-------YLPFSAGPRNCIGQKFALLEL 453
            ..:.:.:..|.::.:.::||..|:||||.|......:       ||.|..|||:|.|.:|||.:|
  Fly   392 DVVTIPVKALHHDPQYYEDPLTFKPERFLESNGGGMKSYRDRGVYLAFGDGPRHCPGMRFALTQL 456

  Fly   454 KTVISKVVRSFEVLPAVDELVSTDGRLN 481
            |..:.:::|:||:  .|:....:|.:::
  Fly   457 KAALVEILRNFEI--KVNPKTRSDNQID 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	112/477 (23%)
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	110/470 (23%)