Protein Alignment Cyp4e3 and LOC3290693

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_563271.1
• Gene: LOC3290693 / 3290693
• VectorBaseID: AGAMI1_003287
• Length: 509
• Species: Anopheles gambiae
• Alignment Length: 580
• Identity: 129/580 - (22%)
• Similarity: 229/580 - (39%)
• Gaps: 138/580 - (23%)

  Fly     3 LAVLALLVLPLITLVYFERKASQRRQLLKEFN-GPTPVPILG--NANRIGKNPAEILSTFFDWWY 64
            |.||.|.|:.|::|.|...::.......:.|. .|:|..:.|  ..|...::.|.:....    |
Mosquito     4 LGVLLLGVVLLLSLAYLFLRSKHNYWRSRGFPCKPSPSLLYGQMQGNGTTRHAAYVTQEI----Y 64

  Fly    65 DYGKDNFLFWIGYS---SHIVMTNPKQLEYILNSQQLIQKSTIYD--LLH-----------PWLG 113
            .|.:|....::|||   ..|||         :...:|::...:.|  :.|           |..|
Mosquito    65 RYAQDRGERYMGYSFFFMPIVM---------VCDIELVKTVLVKDFAVFHDRGMYSNPRADPLSG 120

  Fly   114 HGLLTSFGSKWHKHRKMITPSFHFNILQDFH----EVMNENSAKFMTQLKKASAGDTIIDFQEHA 174
            : |....|.:|...|:.:||:|....::...    :|..|.....:.|:      |..::.:...
Mosquito   121 N-LFALEGHEWRALRQKLTPTFTSGRMKQMFGTMLQVATELHRHLLEQI------DRELEMKAVL 178

  Fly   175 NYLTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKT 239
            ...|.|||...|.|:..|.:...||..::..|.: :...|.|.     ....|::.....|.:..
Mosquito   179 ARFTTDVIGTCAFGIECNTLRNPDSDFLKYGRRV-FEHRMLAM-----VKMTFAMLFRAQAVKLG 237

  Fly   240 LKTLQD--------FTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLL------------- 283
            :|...|        ..:|.:|.|.   :||..:.|           ||:.||
Mosquito   238 VKVTDDDLEAFFMNLVHDTVEHRE---RNGVQRND-----------FLNLLLQIKNKGCLEEQEQ 288

  Fly   284 --SSTIDGRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMN 346
              |::.|...:|..|:..:|..|...|.:|:::.::|.:|.|:::|.:|.:|..|        :|
Mosquito   289 EGSASADRTGMTMNELAAQVFIFFVAGFETSSTVMNFCLYELAKNPHIQERLRDE--------LN 345

  Fly   347 RSV-------SFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGS--IVPKGTTLNLAL 402
            ||:       ::..:...:||...:.|..|.||.:....|...:||.|.|:  ::|:...:.:.:
Mosquito   346 RSIDANGGELTYDMVMGHEYLGQVVNETLRKYPPLETTLRVAGQDYTIPGTRHVIPRHVGVQIPV 410

  Fly   403 ILLGYNDRIFKDPHHFRPERFEEE---KPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSF 464
            ..:.::...:.:|..|.|:||..|   ...|:.:|||..|||.|||.:|.::::|..:..:||:|
Mosquito   411 YAIHHDPAHYPEPECFDPDRFSAEACRNRTPYTFLPFGEGPRVCIGMRFGMMQVKVGLVSMVRAF 475

  Fly   465 EVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKYDP---ILSAVLTLKSDNGLHLRL 521
            ..||...               .||        |..:||   |||..      .|.:||:
Mosquito   476 RFLPTAQ---------------TPD--------RIVFDPKSFILSPA------GGNYLRI 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	111/508 (22%)
LOC3290693	XP_563271.1	CYP6-like	70..501	CDD:410679	109/503 (22%)