Protein Alignment Cyp4e3 and Cyp4d2

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 533
• Identity: 206/533 - (38%)
• Similarity: 307/533 - (57%)
• Gaps: 56/533 - (10%)

  Fly     8 LLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRI-GKNPAEILSTFFDWWYDYGKDN- 70
            ||::...||:.::  ...||:......||.|:|.|||.... |.:|.:|:        |:.|.|
  Fly     8 LLLVAFATLLLWD--FLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIM--------DFVKKNQ 62

  Fly    71 ------FLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHKHRK 129
                  :..||.:...:..|:|:.:|::|:|||.|.|:.:|.||:.|||.|||.|.|.|||..||
  Fly    63 RKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRK 127

  Fly   130 MITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPINAM 194
            :|||:|||.||:.|.|:.::.||..:.||:..:.|.|.|:.........||:|.:||||..|||.
  Fly   128 IITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINAQ 192

  Fly   195 EQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLT--PEFSAYQKTLKTLQDFTYDIIEKRVYA 257
            :..:...|||..|:...:..|..|.::|.:.:|.||  .|.....|.:|.:.|||.:||.:|...
  Fly   193 KNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRET 257

  Fly   258 LQNGGSKEDHDPSL----PRKKMAFLDTLLSSTIDGRPLTRQEIYEEVSTFMFEGHDTTTSGVSF 318
            |.|...:...:..:    .:::||.||.||.|||||.||:.::|.|||.||||||||||||.:||
  Fly   258 LVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISF 322

  Fly   319 SVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDK 383
            .:|.:||||:||::|.:|..:|:|.|....|:.:::.::|:::..|||:.|::|.||.|||:..:
  Fly   323 CLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAE 387

  Fly   384 DYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKPA--PFEYLPFSAGPRNCIGQ 446
            |.:|.|..:|.||...:.:.:|..:...|:.|..||||||:.:.|.  |:.|:||||||||||||
  Fly   388 DVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQIHPYAYIPFSAGPRNCIGQ 452

  Fly   447 KFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKYDPILSAVLTL 511
            |||:||:|:.:||::|.||:||               ||..|         ||      |..:.|
  Fly   453 KFAMLEMKSTVSKLLRHFELLP---------------LGPEP---------RH------SMNIVL 487

  Fly   512 KSDNGLHLRLRER 524
            :|.||:||.|:.|
  Fly   488 RSANGVHLGLKPR 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	185/465 (40%)
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	183/458 (40%)