Protein Alignment Cyp4e3 and Cyp26c1

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_217935.3
• Gene: Cyp26c1 / 308190
• RGDID: 1308843
• Length: 518
• Species: Rattus norvegicus
• Alignment Length: 497
• Identity: 103/497 - (20%)
• Similarity: 191/497 - (38%)
• Gaps: 114/497 - (22%)

  Fly    61 DW------------WYDYGKDNFLFWI----------------GYSSHIV------MTNPKQLEY 91
            ||            |..:|:.  |.|:                .:.:|::      ::..:.:..
  Rat    42 DWASTLPLPKGSMGWPFFGET--LHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRT 104

  Fly    92 ILNSQQLIQKSTIYDLLHPWLG-HGLLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFM 155
            ||..:..:.:|......|..|| |.||.:.|.:..:.||::...|....|:.|...:.|   ...
  Rat   105 ILLGEHRLVRSQWPQSAHILLGSHTLLGAVGERHRQRRKVLARVFSRPALEQFVPRLQE---ALR 166

  Fly   156 TQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPF 220
            .:::...|....:...:.|..||..:.....:|:.::  |.|.:.:.|.|..:..|:
  Rat   167 REVRSWCAAQRPVAVYQAAKALTFRMAARILLGLQLD--EARCTELAQTFERLVENL-------- 221

  Fly   221 KRSNRVFSLTPE--FSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLL 283
                  |||..:  ||..:|.::........:.|.....|:...:.|..|.         |..::
  Rat   222 ------FSLPLDVPFSGLRKGIRARDQLYQHLDEVIAEKLREELTAEPGDA---------LHLII 271

  Fly   284 SSTID-GRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYRE----------- 336
            :|..: ||.|:.||:.|.....:|....||.|..:..:.||.:||....|:.:|
  Rat   272 NSARELGRELSVQELKELAVELLFAAFFTTASASTSLILLLLQHPAAIAKIQQELSAQGLGSPCS 336

  Fly   337 ------------QCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDING 389
                        .||   .|::.:|    :.:::|:|..:||..|:.|.|....|...:.::::|
  Rat   337 CAPRASGSRPDCSCE---PDLSLAV----LGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDG 394

  Fly   390 SIVPKGTTLNLALILLGYNDRIFKD-PHHFRPERFEEEKP------APFEYLPFSAGPRNCIGQK 447
            ..:|||.::..::........:::. |..|.||||..|..      ..|.|:||..|.|:|:||:
  Rat   395 YQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESEDARGSGGRFHYIPFGGGARSCLGQE 459

  Fly   448 FALLELKTVISKVVR---------SFEVLPAVDELVSTDGRL 480
            .|...|:.:..::||         :|.|:..|..:...||.|
  Rat   460 LAQAVLQLLAVELVRTARWELATPAFPVMQTVPIVHPVDGLL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	99/478 (21%)
Cyp26c1	XP_217935.3	cytochrome_P450	59..504	CDD:477761	100/480 (21%)