Protein Alignment Cyp4e3 and cyp19a1a

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_571229.4
• Gene: cyp19a1a / 30390
• ZFINID: ZDB-GENE-990415-43
• Length: 517
• Species: Danio rerio
• Alignment Length: 512
• Identity: 112/512 - (21%)
• Similarity: 203/512 - (39%)
• Gaps: 99/512 - (19%)

  Fly     4 AVLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFDWWYDYGK 68
            |.:.||:|.|:..:...|              |....|.|.:...|..|......|
Zfish    44 ATILLLLLCLLLAIRHHR--------------PHKSHIPGPSFFFGLGPVVSYCRF--------- 85

  Fly    69 DNFLFWIGYSSHIVMTNPKQLEYI---LNSQQ---LIQKSTIYDLLHPWLGHGLLTS-FGSK--- 123
                .|.|..:.....|.|..:.:   :|.::   |.:.|.:|.:|.    ..|.|| ||||
Zfish    86 ----IWSGIGTASNYYNSKYGDIVRVWINGEETLILSRSSAVYHVLR----KSLYTSRFGSKLGL 142

  Fly   124 ------------------WHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDF 170
                              |.|.|.....:.....||...|:...::...:..|.:.:.....:|.
Zfish   143 QCIGMHEQGIIFNSNVALWKKVRAFYAKALTGPGLQRTMEICTTSTNSHLDDLSQLTDAQGQLDI 207

  Fly   171 QEHANYLTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFK----RSNRVFSLTP 231
            ......:.:||.....:|||:|.            .|:...|: :.|..::    :.:..|.|..
Zfish   208 LNLLRCIVVDVSNRLFLGVPLNE------------HDLLQKIH-KYFDTWQTVLIKPDVYFRLDW 259

  Fly   232 EFSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDGRPLTRQE 296
            ....:::..:.|||....:||::...|.: ..|.||        :.|...|:.:...|. |:.:.
Zfish   260 LHKKHKRDAQELQDAITALIEQKKVQLAH-AEKLDH--------LDFTAELIFAQSHGE-LSAEN 314

  Fly   297 IYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLD 361
            :.:.|...:....||.:..:.|.:.||.::|||:.|:.:|...|:.   .:|:....::|::.|:
Zfish   315 VRQCVLEMVIAAPDTLSISLFFMLLLLKQNPDVELKILQEMDSVLA---GQSLQHSHLSKLQILE 376

  Fly   362 LFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTT--LNLALILLGYNDRIFKDPHHFRPERFE 424
            .||.|:.|.:|.|.|..|....|..|.|..|.|||.  ||:..:   :....|..|:.|..:.|:
Zfish   377 SFINESLRFHPVVDFTMRRALDDDVIEGYNVKKGTNIILNVGRM---HRSEFFSKPNQFSLDNFQ 438

  Fly   425 EEKPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLP----AVDELVSTD 477
            :..|:.| :.||.:|||:|:|:..|::.:|:::..::..|.|.|    .|:.:..|:
Zfish   439 KNVPSRF-FQPFGSGPRSCVGKHIAMVMMKSILVALLSRFSVCPMKACTVENIPQTN 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	100/448 (22%)
cyp19a1a	NP_571229.4	None