Protein Alignment Cyp4e3 and Cyp4f39

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_234837.3
• Gene: Cyp4f39 / 299566
• RGDID: 1308796
• Length: 550
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 155/547 - (28%)
• Similarity: 279/547 - (51%)
• Gaps: 74/547 - (13%)

  Fly     5 VLALLVLPLITLVYFERKASQRRQLLKEFN------GPTPVP-----ILGN-----ANRIG-KNP 52
            ||:.|:|.|:.|::  |...|..:|..:|.      ...|.|     :||:     .|..| :|.
  Rat    23 VLSALLLFLLFLLF--RLLLQAFKLFSDFRITCRRLSCFPEPPGRHWLLGHMSMYLPNEKGLQNE 85

  Fly    53 AEILSTFFDWWYDYGKDNFLFWIG-YSSHIVMTNPKQLEYILNSQQLI--QKSTIYDLLHPWLGH 114
            .::|.|.        ....|.|:| :...:|:.:|..::.:|.:...|  :....|..|.||||.
  Rat    86 KKVLDTM--------HHIILAWVGPFLPLLVLVHPDYIKPVLGASAAIAPKDEFFYSFLKPWLGD 142

  Fly   115 GLLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNEN----SAKFMTQLKKASAGDTIIDFQEHAN 175
            |||.|.|:||.:||:::||:|||:||:.:.::.|::    .||:...|.:.|.  |..|..||.:
  Rat   143 GLLISKGNKWSRHRRLLTPAFHFDILKPYMKIFNQSVNIMHAKWRRHLAEGSV--TSFDMFEHVS 205

  Fly   176 YLTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTL 240
            .:|||.:.........:..|:. |..:.:..::...:..|.:......:.::.||.:...:::..
  Rat   206 LMTLDSLQKCVFSYSSDCQEKL-SDYISSIIELSALVVRRQYRLHHYLDFIYYLTADGRRFRQAC 269

  Fly   241 KTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDT-LLSSTIDGRPLTRQEIYEEVSTF 304
            .|:.:||.::|::|..||:..|: |....:...|.:.|:|. ||:...:|:.|:.::|..|..||
  Rat   270 DTVHNFTTEVIQQRRRALRELGA-EAWLKAKQGKTLDFIDVLLLAKDEEGKELSDEDIRAEADTF 333

  Fly   305 MFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVM-GHDMNRSVSFQEIAKMKYLDLFIKEAQ 368
            ||||||||:||:|::::.|:::|:.|.|...|..||| |.:: ..:.:.::.::.:..:.|||:.
  Rat   334 MFEGHDTTSSGLSWALFNLAKYPEYQDKCREEIQEVMKGREL-EELDWDDLTQLPFTTMCIKESL 397

  Fly   369 RVYPSVPFIGRYCDKDYDI-NGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKP---A 429
            |.:|.|..|.|.|.:|..: :|.|:|||....:::....||..::.|...:.|.||:.:.|   :
  Rat   398 RQFPPVTLISRRCTEDIKLPDGRIIPKGIICLVSIYGTHYNPLVWPDSKVYNPYRFDPDIPQQRS 462

  Fly   430 PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKR 494
            |..::||||||||||||.||:.|::.|::..:..|.:  :||.                ..|::|
  Rat   463 PLAFVPFSAGPRNCIGQSFAMAEMRVVVALTLLRFRL--SVDR----------------TRKVRR 509

  Fly   495 EAGRHKYDPILSAVLTLKSDNGLHLRL 521
            :           ..|.|:::|||.|.:
  Rat   510 K-----------PELILRTENGLWLNV 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	135/463 (29%)
Cyp4f39	XP_234837.3	CYP4F	82..523	CDD:410772	138/482 (29%)