Protein Alignment Cyp4e3 and Cyp4f5

DIOPT Version :9

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_775147.1
• Gene: Cyp4f5 / 286905
• RGDID: 708364
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 500
• Identity: 142/500 - (28%)
• Similarity: 250/500 - (50%)
• Gaps: 62/500 - (12%)

  Fly    42 LGNANRIGKNP------AEILSTFFDWWYDYGKDNFLFWIGYSSHIV-MTNPKQLEYILNSQQLI 99
            ||:...|..|.      .|:..||        :|..|.|:|....:: :.:|..:..:|.:..|:
  Rat    61 LGHLGTIQSNEEGMRLVTEMGQTF--------RDIHLCWLGPVIPVLRLVDPAFVAPLLQAPALV 117

  Fly   100 --QKSTIYDLLHPWLGHGLLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNEN----SAKFMTQL 158
              :.:|....|.||||.||..|.|.||.:||:::||:|||:||:.:.::.|::    .||:....
  Rat   118 APKDTTFLRFLKPWLGDGLFLSSGDKWSRHRRLLTPAFHFDILKPYVKIFNQSVNIMHAKWKHLC 182

  Fly   159 KKASAGDTIIDFQEHANYLTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRS 223
            .:.||.   ::..|:.:.:|||.:.....|...|..|. .|..:.|..::...|..|:...|...
  Rat   183 LEGSAR---LEMFENISLMTLDSLQKCLFGFDSNCQES-PSEYISAILELSSLIIKRSQQLFLYL 243

  Fly   224 NRVFSLTPEFSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKE--DHDPSLPRKKMAFLDTLLSST 286
            :.::..|.:...::|....:.:||..:|.:|...|.:.|:.|  :.......|.:.|:|.||.:.
  Rat   244 DFLYYRTADGRRFRKACDLVHNFTDAVIRERRRLLSSQGTDEFLESKTKSKSKTLDFIDVLLLAK 308

  Fly   287 ID-GRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVS 350
            .: |:.|:.::|..|..||||.|||||.|.:|:.:|.|:|||:.|.:..:|..|::.......:.
  Rat   309 DEHGKELSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVWELLRDREPEEIE 373

  Fly   351 FQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDI-NGSIVPKGTTLNLALILLGYNDRIFKD 414
            :.::|::.:|.:.|||:.|::|....:.|.|.:|..: :|.::|||....:::..:.:|..::.|
  Rat   374 WDDLAQLPFLTMCIKESLRLHPPAIDLLRRCTQDIVLPDGRVIPKGNICVISIFGIHHNPSVWPD 438

  Fly   415 PHHFRPERFEEE---KPAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVST 476
            |..|.|.||:.|   |.:|..::||||||||||||.||:.|:|.|::..:..|.||
  Rat   439 PEVFDPFRFDSENRQKRSPLSFIPFSAGPRNCIGQTFAMNEMKVVVALTLLRFRVL--------- 494

  Fly   477 DGRLNTYLGLAPDEKLKREAGRHKYDPILSAVLTLKSDNGLHLRL 521
                       ||:|          :|.....:.|:::.||.||:
  Rat   495 -----------PDDK----------EPRRKPEIILRAEGGLWLRM 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	132/445 (30%)
Cyp4f5	NP_775147.1	p450	52..516	CDD:278495	140/496 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348556
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.640