Protein Alignment Cyp4e3 and Cyp4f6

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_006241111.1
• Gene: Cyp4f6 / 266689
• RGDID: 708365
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 536
• Identity: 154/536 - (28%)
• Similarity: 260/536 - (48%)
• Gaps: 87/536 - (16%)

  Fly    36 PTPVPILGNANRIGKNPAEILS---TFFD---------------WWYDY---------------- 66
            |..:.:||.|:.|   .|.||:   ||:|               |::.:
  Rat    19 PWHLLLLGGASWI---LARILAWIYTFYDNCCRLRCFPQPPKPSWFWGHLTLMKNNEEGMQFIAH 80

  Fly    67 ----GKDNFLFWIGYSSHIV-MTNPKQLEYILNSQQLI--QKSTIYDLLHPWLGHGLLTSFGSKW 124
                .:|..|.|:|....|: :.:|..:..:|.:...:  ::.|:|..|.||||.|||.|.|.||
  Rat    81 LGRNFRDIHLSWVGPVYPILRLVHPNVIAPLLQASAAVAPKEMTLYGFLKPWLGDGLLMSAGEKW 145

  Fly   125 HKHRKMITPSFHFNILQDFHEVMNEN----SAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDT 185
            :.||:::||:|||:||:.:.::.|::    .||:.....|.||.   :|..||.:.:|||.:...
  Rat   146 NHHRRLLTPAFHFDILKSYVKIFNKSVNTMHAKWQRLTAKGSAR---LDMFEHISLMTLDSLQKC 207

  Fly   186 AMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQDFTYDI 250
            ......|..|. :|..:.|..::...|..|...||...:.::.||.:...::|....:.:||..:
  Rat   208 IFSFDSNCQES-NSEYIAAILELSSLIVKRQRQPFLYLDFLYYLTADGRRFRKACDVVHNFTDAV 271

  Fly   251 IEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTID-GRPLTRQEIYEEVSTFMFEGHDTTTS 314
            |.:|...|...|..|........|.:.|:|.||.:..: |:.|:..:|..|..||||.|||||.|
  Rat   272 IRERRSTLNTQGVDEFLKARAKTKTLDFIDVLLLAKDEHGKGLSDVDIRAEADTFMFGGHDTTAS 336

  Fly   315 GVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGR 379
            .:|:.:|.|:|||:.|.:..:|..|::.......:.:.::|::.:|.:.|||:.|::|.|..|.|
  Rat   337 ALSWILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVLLISR 401

  Fly   380 YCDKDYDI-NGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKP---APFEYLPFSAGP 440
            .|.:|..: :|.::|||....:::..:.:|..::.||..:.|.||:.|.|   :|..::||||||
  Rat   402 CCSQDIVLPDGRVIPKGNICVISIFGVHHNPSVWPDPEVYNPFRFDPENPQKRSPLAFIPFSAGP 466

  Fly   441 RNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKYDPIL 505
            ||||||.||:.|:|..::..:..|.||                    ||:|          :|..
  Rat   467 RNCIGQTFAMSEIKVALALTLLRFCVL--------------------PDDK----------EPRR 501

  Fly   506 SAVLTLKSDNGLHLRL 521
            ...|.|:::.||.||:
  Rat   502 KPELILRAEGGLWLRV 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	140/462 (30%)
Cyp4f6	XP_006241111.1	CYP4F	75..516	CDD:410772	140/474 (30%)