Protein Alignment Cyp4e3 and Cyp51

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_037073.1
• Gene: Cyp51 / 25427
• RGDID: 2481
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 515
• Identity: 125/515 - (24%)
• Similarity: 211/515 - (40%)
• Gaps: 122/515 - (23%)

  Fly     3 LAVLALLVLPLITLVYFERKA-SQRRQLLKEFNGP----TPVPILGNANRIGKNPAEILSTFFDW 62
            |:.|.:.....::|||..|.| ....||......|    :|:|.||:|...||:|.|.|...::
  Rat    27 LSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPYIYSPIPFLGHAIAFGKSPIEFLENAYE- 90

  Fly    63 WYDYGK--------DNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTS 119
              .||.        ..|.:.:|..:..::.|.|..:  ||::::               :|.||
  Rat    91 --KYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNED--LNAEEV---------------YGRLT- 135

  Fly   120 FGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYL------- 177
                        ||.|...:..|   |.|   |.|:.|.|...:|..|..|:::.:.:
  Rat   136 ------------TPVFGKGVAYD---VPN---AVFLEQKKILKSGLNIAHFKQYVSIIEKEAKEY 182

  Fly   178 ---------------TLDVICDTAM----GVPINAMEQRDSSIVQAFRDMCYNINMRA-----FH 218
                           ..::|..||.    |..|.:  |.:..:.|.:.|:....:..|     :.
  Rat   183 FKSWGESGERNVFEALSELIILTASHCLHGKEIRS--QLNEKVAQLYADLDGGFSHAAWLLPGWL 245

  Fly   219 PFKRSNRVFSLTPEFSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLL 283
            |.          |.|....:..:.:::..|..|:||..      |||..:.        .|.|||
  Rat   246 PL----------PSFRRRDRAHREIKNIFYKAIQKRRL------SKEPAED--------ILQTLL 286

  Fly   284 SSTI-DGRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNR 347
            .||. ||||||..||...:...:..|..|:::..::..:.|:|...:|.|.|.||..|.|.|: .
  Rat   287 DSTYKDGRPLTDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDKPLQDKCYLEQKTVCGEDL-P 350

  Fly   348 SVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIF 412
            .::::::..:..||..|||..|:.|.:..:.|.......:.|..:|.|..:.::..:   |.|:
  Rat   351 PLTYEQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGYTIPPGHQVCVSPTV---NQRL- 411

  Fly   413 KDPH----HFRPERFEEEKPA---PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFE 465
            ||..    .|.|:|:.::.||   .|.|:||.||...|||:.||.:::||:.|.::|.:|
  Rat   412 KDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYE 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	103/445 (23%)
Cyp51	NP_037073.1	CYP51-like	88..499	CDD:410668	105/454 (23%)