Protein Alignment Cyp4e3 and erg11

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_592990.1
• Gene: erg11 / 2542599
• PomBaseID: SPAC13A11.02C
• Length: 495
• Species: Schizosaccharomyces pombe
• Alignment Length: 480
• Identity: 112/480 - (23%)
• Similarity: 189/480 - (39%)
• Gaps: 91/480 - (18%)

  Fly    39 VPILGNANRIGKNPAEILSTFF-DWWYDYGKDNFLF---------WIGYSSHIVMTNPKQLEYIL 93
            :|.:|:|...|.:|    ..|| :....|| |.|.|         ::|...:..:.|.|..:  |
pombe    40 IPFVGSAVAYGMDP----YVFFRECRAKYG-DVFTFVCMGRKMTAFLGVQGNDFLFNGKLAD--L 97

  Fly    94 NSQQ--------LIQKSTIYDLLHPWLGHGLLTSFGSKWHKHRKMITPSFHFNILQDFHE-VMNE 149
            |:::        :..|..:||:.:    |..:        :|:|.|.....|:..:.:.. ::||
pombe    98 NAEEAYSHLTTPVFGKDVVYDIPN----HVFM--------EHKKFIKSGLGFSQFRSYVPLILNE 150

  Fly   150 NSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINM 214
            ..|...|........:.:.|..:....:|:.....|..|..:.      ......|.|:.::::
pombe   151 MDAFLSTSPDFGPGKEGVADLLKTMPVMTIYTASRTLQGAEVR------KGFDAGFADLYHDLD- 208

  Fly   215 RAFHPFKRSNRVFSL--TPEFSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMA 277
            :.|.|.   |.||..  .|......:..|.:|.....||:.|..:.:|.|:.
pombe   209 QGFSPV---NFVFPWLPLPRNRRRDRAHKIMQKTYLKIIKDRRSSTENPGTD------------- 257

  Fly   278 FLDTLLSSTI-DGRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVM 341
            .:.||:|... |||||...||...:...:..|..|:.:.:.:.:.||...|::...|:.||..|:
pombe   258 MIWTLMSCKYRDGRPLKEHEIAGMMIALLMAGQHTSAATIVWVLALLGSKPEIIEMLWEEQKRVV 322

  Fly   342 GHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDINGS--IVPKGTTLNLALIL 404
            |.  |..:.|.:...|..|:..|:|..|::|.:....|...:|..:.||  ::|....|..|..|
pombe   323 GE--NLELKFDQYKDMPLLNYVIQETLRLHPPIHSHMRKVKRDLPVPGSKIVIPANNYLLAAPGL 385

  Fly   405 LGYNDRIFKDPHHFRPERF-----EEE-------------KPAPFEYLPFSAGPRNCIGQKFALL 451
            ....:..|.....|.|:|:     |:|             |.|...||||.||...|||::||.:
pombe   386 TATEEEYFTHATDFDPKRWNDRVNEDENAEQIDYGYGLVTKGAASPYLPFGAGRHRCIGEQFAYM 450

  Fly   452 ELKTVISKVVRSFE-----VLPAVD 471
            .|.|:|||.|..:.     .:|.||
pombe   451 HLSTIISKFVHDYTWTLIGKVPNVD 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	103/450 (23%)
erg11	NP_592990.1	CYP51-like	60..492	CDD:410668	105/456 (23%)