Protein Alignment Cyp4e3 and erg5

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_593788.2
• Gene: erg5 / 2542469
• PomBaseID: SPAC19A8.04
• Length: 543
• Species: Schizosaccharomyces pombe
• Alignment Length: 420
• Identity: 98/420 - (23%)
• Similarity: 168/420 - (40%)
• Gaps: 72/420 - (17%)

  Fly    77 YSSHIVMTNPKQL-EYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWH-KHRKMITPSFHFNI 139
            :...:|:.:.:.| ..||||...:|...: |.....|.|........:.| ::||.:...|....
pombe    93 FHKFVVIASERDLARKILNSPSYVQPCVV-DAGKKILKHTNWVFLDGRDHIEYRKGLNGLFTTRA 156

  Fly   140 LQDF----HEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPIN-------- 192
            |..:    ..|.|:...:|:...|...| ..:|.|::    :.:...|.|..|..|:
pombe   157 LASYLPAQEAVYNKYFKEFLAHSKDDYA-QYMIPFRD----INVATSCRTFCGYYISDDAIKHIA 216

  Fly   193 --------AMEQRDSSIVQAFRDMCYNIN-----MRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQ 244
                    |||..:..||..|..:.|.|.     ||.|......:|     ....|.......::
pombe   217 DEYWKITAAMELVNFPIVLPFTKVWYGIQSRKVVMRYFMKAAAESR-----KNMEAGNAPACMME 276

  Fly   245 DFTYDIIEKRVYALQN--GGSKEDHDPSLPRKKMAFLDTLLSSTIDGRPLTRQEIYEEVS----T 303
            ::.:::||.|.|..:|  |..|    ||:                    |.|:...||:|    :
pombe   277 EWIHEMIETRKYKSENKEGAEK----PSV--------------------LIREFSDEEISLTFLS 317

  Fly   304 FMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQ 368
            |:|...|.|:|.:::...||:.||||.:|:..||..:...|::..:|...:.||.|....:||..
pombe   318 FLFASQDATSSAMTWLFQLLADHPDVLQKVREEQLRIRKGDIDVPLSLDLMEKMTYTRAVVKECL 382

  Fly   369 RVYPSVPFIGRYCDKDYDINGS-IVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEE---KPA 429
            |:.|.|..:.....|.:.|... .|||...:...|....::.:::.:|..|.|:|:...   :.:
pombe   383 RLRPPVLMVPYRVKKAFPITPDYTVPKDAMVIPTLYGALHDSKVYPEPETFNPDRWAPNGLAEQS 447

  Fly   430 PFEYLPFSAGPRNCIGQKFALLELKTVISK 459
            |..::.|..||..|:||::|:..|...|.|
pombe   448 PKNWMVFGNGPHVCLGQRYAVNHLIACIGK 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	98/420 (23%)
erg5	NP_593788.2	CYP61_CYP710	85..507	CDD:410703	98/420 (23%)