Protein Alignment Cyp4e3 and Cyp4a2

DIOPT Version :9

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_038965182.1
• Gene: Cyp4a2 / 24306
• RGDID: 2479
• Length: 517
• Species: Rattus norvegicus
• Alignment Length: 544
• Identity: 152/544 - (27%)
• Similarity: 257/544 - (47%)
• Gaps: 70/544 - (12%)

  Fly     4 AVLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFDWWYDYGK 68
            |.|..|.|.|...|.|..:.....:.|::|.. ||...|...|...:...::|:     |.:...
  Rat    22 AFLLSLFLVLFKAVQFYLRRQWLLKALEKFPS-TPSHWLWGHNLKDREFQQVLT-----WVEKFP 80

  Fly    69 DNFLFWI-GYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHKHRKMIT 132
            ...|.|: |.::.:::.:|..::.:|....    ...|..|.||:|:|||...|.||.:||:|:|
  Rat    81 GACLQWLSGSTARVLLYDPDYVKVVLGRSD----PKPYQSLAPWIGYGLLLLNGKKWFQHRRMLT 141

  Fly   133 PSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMG------VPI 191
            |:||::||:.:.::|.::.:..:.:.:|....|..::...:.:.:|||.:...|..      :.:
  Rat   142 PAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDV 206

  Fly   192 N------AMEQRDSSIV----QAF--RDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQ 244
            |      |:|..::.|.    .||  ..:.||::...    :.|.|...:..|.:.....|....
  Rat   207 NSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDG----RLSRRACQIAHEHTGSVFLLPAFL 267

  Fly   245 DFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTI-DGRPLTRQEIYEEVSTFMFEG 308
            ..:..:|:.|...|||   :|:...:..::.:.|||.||.:.: ||:.|:.:::..||.||||||
  Rat   268 SLSDGVIKTRKAQLQN---EEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEG 329

  Fly   309 HDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPS 373
            ||||.||:|:..|.|:.||:.|.:...|...::|.  ..||::..:.:|.|..:.||||.|:|..
  Rat   330 HDTTASGISWVFYALATHPEHQERCREEVQSILGD--GTSVTWDHLDQMPYTTMCIKEALRLYSP 392

  Fly   374 VPFIGRYCDKDYDI-NGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKPA-PFEYLPF 436
            ||.:.|........ :|..:|||..:.:.:..|.:|...:.:|..|.|.||..:.|. ...||||
  Rat   393 VPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPF 457

  Fly   437 SAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKY 501
            |.|.|||||::||:.|||..::..:..||:||....:
  Rat   458 SGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRI---------------------------- 494

  Fly   502 DPILSAVLTLKSDNGLHLRLRERR 525
             |:....|.|||.||:||||::.|
  Rat   495 -PVPMPRLVLKSKNGIHLRLKKLR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	129/454 (28%)
Cyp4a2	XP_038965182.1	CYP4B-like	69..512	CDD:410771	135/489 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348475
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650