Protein Alignment Cyp4e3 and cyp-13A2

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 578
• Identity: 134/578 - (23%)
• Similarity: 231/578 - (39%)
• Gaps: 129/578 - (22%)

  Fly     3 LAVLALLVLPLITL-----VYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFDW 62
            |||...:.|.::|.     .|:.||.         ..||...|.:|..:.:.::....|....:|
 Worm     7 LAVTFSIFLGILTYYLWIWTYWMRKG---------VKGPRGRPFVGVLDVLLEHETPGLIKLGEW 62

  Fly    63 WYDYGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYD-----LLHPWLGH-------G 115
            ...||| .:.:..|....:|:.:|..:..|...|        :|     .|:|..|:       .
 Worm    63 TKKYGK-VYGYTDGTQRTLVVADPAMVHEIFVKQ--------FDNFYGRKLNPIQGNPEKEQRVH 118

  Fly   116 LLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLD 180
            ||.:.|.:|.:.|.:.:.||....|:.....:.:::.:.:..::|.:||...||........|:|
 Worm   119 LLAAQGYRWKRLRTISSQSFSNASLKKMKRTVEDSALELLRHIEKQTAGGEQIDMLRFYQEYTMD 183

  Fly   181 VICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSN-----RVF--------SLT-- 230
            ||...|||       |.||.:   |::...|: :|......|.|     :||        .||
 Worm   184 VIGRFAMG-------QTDSMM---FKNPIVNV-VREIFCGSRKNLMLICQVFPPIGQFIRDLTFK 237

  Fly   231 -PEFSAYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDG----- 289
             |...|::     |.....|::..|:...:.....|..:|      ..|:|..|.:..|.
 Worm   238 FPRIPAFK-----LYSIMQDVVAARIAQREREKGAESGEP------QDFIDLFLDARSDDVDFSA 291

  Fly   290 --------------RPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEV 340
                          :.|:..|:..:...|:..|.|||...:|:..|||:.:|.:|.|:..|....
 Worm   292 EAREDFSKRNLKITKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIARE 356

  Fly   341 MGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFI-GRYCDKDYDINGSIVPKGTTLNLALIL 404
            .|   ...|.|:::.::||:|..||||.|:||..... .|.|.|...:||..:..|..:.:....
 Worm   357 FG---TSEVEFEKLGRLKYMDCVIKEALRLYPLASISNSRKCMKTTTVNGVKIEAGVYVQMDTWS 418

  Fly   405 LGYNDRIF-KDPHHFRPERFEEEKPAPFE--YLPFSAGPRNCIGQKFALLELKTVISKVVRSFEV 466
            |.|:..:: :|...|:|||:..::|...:  ||||..|||.|||.:.|::|.|.:::.:::::
 Worm   419 LHYDPELWGEDVKEFKPERWSTDEPLEHKGAYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNY-- 481

  Fly   467 LPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKYDP--ILSAVLTLKSDNGLHLRLR 522
                           |:           |.|.....|  ::.:..|...|..:|||.|
 Worm   482 ---------------TF-----------ETGNKTRIPLKLVGSATTSPEDVFVHLRPR 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	114/503 (23%)
cyp-13A2	NP_496109.1	CYP3A-like	65..508	CDD:410678	116/504 (23%)