Protein Alignment Cyp4e3 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 529
• Identity: 137/529 - (25%)
• Similarity: 229/529 - (43%)
• Gaps: 124/529 - (23%)

  Fly     4 AVLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRI--GKNPAEILSTFFDWWYDY 66
            :::.:|...|.|..|::|:.         ..||:..||||:|..:  .:||..:  ...:|...|
 Worm    11 SIIGVLSFYLWTWSYWKRRG---------IAGPSGYPILGSALEMLSSENPPYL--QLKEWTKQY 64

  Fly    67 GKDNFLFWI--GYSSHIVMTNPKQLEYILNSQQLIQKSTIYD-----LLHPWLGH-------GLL 117
            ||   ::.|  |.|..:|:::|..::.:...|        ||     .|:|..|.       .|.
 Worm    65 GK---VYGITEGLSRTLVISDPDLVQEVFVKQ--------YDNFFGRKLNPIQGDPNKDKRVNLF 118

  Fly   118 TSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVI 182
            :|.|.:|.:.|.:.:|:|..|.|:.....:.|.:.:.:..:::.:.|...||..:.....|||||
 Worm   119 SSQGHRWKRLRTISSPTFSNNSLRKLKTTVEECAVELLRHIEQHTDGGQPIDLLDFYQEFTLDVI 183

  Fly   183 CDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVF-----------SLTPEFS-A 235
            ...|||       |.||   |.|::        ...|:.|:  ||           ||.|... .
 Worm   184 GRIAMG-------QTDS---QMFKN--------PLLPYVRA--VFGEPRKGLFLSGSLAPWIGPI 228

  Fly   236 YQKTLKTLQDF-----------TYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDG 289
            .:..:.:|.:.           |.:.:|:|| .|:....|...||..|:.   |:|..|.:..|.
 Worm   229 LRMVMFSLPNIVKNPAVHVIRHTSNAVEQRV-KLRMADEKAGIDPGEPQD---FIDLFLDAKSDD 289

  Fly   290 -----------------RPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYRE- 336
                             |.||.:||..:...|:..|.|||...:|:|.:||:.||.||:||..|
 Worm   290 VELENNEDFTKAGVKVTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEI 354

  Fly   337 --QCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIG-----RYCDKDYDINGSIVPK 394
              :|      .:..|:|.:::|:||::..|||..|:||    :|     |.|.:...|....:.:
 Worm   355 DREC------ADPEVTFDQLSKLKYMECVIKETLRMYP----LGALANSRCCMRATKIGNYEIDE 409

  Fly   395 GTTLNLALILLGYNDRIF-KDPHHFRPERFEEEKPAPFE---YLPFSAGPRNCIGQKFALLELKT 455
            ||.:......|..:..|: :|...|:|||:|......::   |:||..|||.|||.:.|.:|.|.
 Worm   410 GTNILCDTWTLHSDKSIWGEDAEEFKPERWESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKL 474

  Fly   456 VISKVVRSF 464
            ::|.::|.:
 Worm   475 LLSHILRKY 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	120/463 (26%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	122/466 (26%)