Protein Alignment Cyp4e3 and cyp-13A11

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_499704.1
• Gene: cyp-13A11 / 184472
• WormBaseID: WBGene00008809
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 132/524 - (25%)
• Similarity: 224/524 - (42%)
• Gaps: 104/524 - (19%)

  Fly     3 LAVLALLVLPLITLV--YFERKASQRRQLLKEFNGPTPVPILGNANRI--GKNPAEILSTFFDWW 63
            :.:|..:|..::.:|  ||......||..:.   ||...|.||:|..:  .:||..:  ....|.
 Worm     1 MIILLFVVSSVVGIVSYYFWTWTYWRRCGIP---GPQGYPFLGSALDMMDHENPPFL--QLKKWT 60

  Fly    64 YDYGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTI--YD-----LLHPWLGH------- 114
            ..|||     ..|.:..::.|      .:::...||.:..:  ||     .|:|..|.
 Worm    61 SQYGK-----VYGITEGLLRT------LVISDTNLIHEVFVKQYDNFYGRNLNPIQGDPNREKRV 114

  Fly   115 GLLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTL 179
            .|.::.|.:|.:.|.:..|:|..|.|:.....:.:::.:.:..:::.:||...||..|:....|:
 Worm   115 TLFSAQGHRWKRLRTIANPTFSSNNLRKIQVTVEDSALELLRHIEQHTAGGKAIDVLEYFQEFTM 179

  Fly   180 DVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAF---------HPFKRSNRVFSLTPEFS- 234
            |||...|||.|.:.|.:  :.::...||:........|         .|..| ..||..|..|:
 Worm   180 DVIGRIAMGQPDSLMFK--NPLLPCARDVFGKPRTALFLSGILFPWIGPMIR-KVVFYFTNVFNN 241

  Fly   235 -----AYQKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDG----- 289
                 .||         |.:.:|:|: ..:....|...||..|:.   |:|..|.:..|.
 Worm   242 PAAQIMYQ---------TANAVEQRI-KQRMAEEKAGIDPGEPQD---FIDLFLDAKSDDMELEN 293

  Fly   290 ------------RPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYRE---QCE 339
                        |.||:.|:..:...|:..|.|||...:|:|.:||:.||..|:||..|   :|
 Worm   294 NEDFTKAGVKVTRQLTKDEVVGQCFVFLIAGFDTTALSLSYSSFLLATHPKAQKKLQEEIDREC- 357

  Fly   340 VMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIG-----RYCDKDYDINGSIVPKGTTLN 399
                 .:..|:|.:::|:||::..|||..|:||    :|     |.|.:...|....:.||..:.
 Worm   358 -----ADPEVTFDQLSKLKYMECVIKETLRMYP----LGALANSRRCMRSTKIGNYEIEKGVDIL 413

  Fly   400 LALILLGYNDRIF-KDPHHFRPERFEEEKPAPFE---YLPFSAGPRNCIGQKFALLELKTVISKV 460
            .....|.|:..|: :|...|:|||:|......::   |:||..|||.|||.:.|.:|.|.::|.:
 Worm   414 CDTWTLHYDKSIWGEDAEEFKPERWESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHI 478

  Fly   461 VRSF 464
            :|.:
 Worm   479 LRKY 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	114/455 (25%)
cyp-13A11	NP_499704.1	CYP3A-like	62..506	CDD:410678	116/458 (25%)