Protein Alignment Cyp4e3 and cyp-13B1

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_510233.1
• Gene: cyp-13B1 / 181462
• WormBaseID: WBGene00008519
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 132/544 - (24%)
• Similarity: 240/544 - (44%)
• Gaps: 122/544 - (22%)

  Fly     4 AVLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRIG--KNPAEILSTFFDWWYDY 66
            |::.|:||......||:...:..|:  :..:||..:|.:||...:.  ..|...|  ...|...:
 Worm     3 AIIVLVVLFATIAGYFKWIHTYWRR--RGISGPEGLPFIGNYYDLADVNKPRGYL--IHKWTQKF 63

  Fly    67 GKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLI---------QKSTIYDLLHPWLGHG------- 115
            || .|.::.|....:|:::...|      |:|.         :|||.:.       ||
 Worm    64 GK-VFGYYEGAVPVLVVSDMDML------QELFLKKFDNFYARKSTNHI-------HGNLECSKS 114

  Fly   116 -----LLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHAN 175
                 |.||.|::|.:.|.:.:|.|....|:..|:||.:::...:..:.|...|.   .|..||.
 Worm   115 EPRINLFTSRGARWKRLRALASPGFSVKALKQVHDVMEDSAINMVDLMAKHEDGK---PFNIHAY 176

  Fly   176 Y--LTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFS-----LTPEF 233
            :  .|.|||...|||.|.:  |..::|.|:..:.:           |.|::||..     |.|:|
 Worm   177 FQEFTYDVISRLAMGQPNS--ELFNNSGVEIVKSI-----------FMRTHRVLPWYFTVLFPQF 228

  Fly   234 SAYQKTL--------------------KTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAF 278
            ....|.:                    ||::    ..|::|....:.|....::|         |
 Worm   229 EHLVKRMFYNHAAVQGGDIEKLLLICKKTVE----SRIQEREENAKLGFENAEND---------F 280

  Fly   279 LDTLLS------------STIDGRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQR 331
            :|..|:            ||:: :.:|.:::......|:..|.|||.:.::::.|||::||: :.
 Worm   281 IDMFLNYYSEQVEDIEFGSTVE-KKVTAEDVIGACFVFLLAGFDTTANSLAYASYLLAKHPE-KM 343

  Fly   332 KLYREQCE-VMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPF-IGRYCDKDYDINGSIVPK 394
            ||.:|:.: |:|   :.:||:.::.|:||||..::|:.|:||...| ..|.|.|...:....:.|
 Worm   344 KLAQEEVDTVVG---SENVSYDDMTKLKYLDAVVRESLRLYPVAWFACSRECVKPTTLGDIYIDK 405

  Fly   395 GTTLNLALILLGYNDRIF-KDPHHFRPERF-EEEKPAPFEYLPFSAGPRNCIGQKFALLELKTVI 457
            |..:...::.|..:..|: ::...|.|||: |........::||.||||.|:|.:..|.|.||.:
 Worm   406 GVKIEADVMSLHRSKEIWGENADDFVPERWLEPSSRHTMSWIPFGAGPRQCVGMRLGLSEAKTAL 470

  Fly   458 SKVVRSFEVLPAVDELVSTDGRLN 481
            :.::|.::::..|:    |:..||
 Worm   471 AHLLRRYDLVAGVE----TEKELN 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	116/478 (24%)
cyp-13B1	NP_510233.1	CYP3A-like	62..500	CDD:410678	117/481 (24%)