Protein Alignment Cyp4e3 and cyp-29A2

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_505847.1
• Gene: cyp-29A2 / 179550
• WormBaseID: WBGene00011830
• Length: 503
• Species: Caenorhabditis elegans
• Alignment Length: 539
• Identity: 182/539 - (33%)
• Similarity: 271/539 - (50%)
• Gaps: 67/539 - (12%)

  Fly     5 VLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRI-GKNPAEILSTFFDWWYDYGK 68
            :||.|...:.||:.::|    ..|...:..||...||.||...| ||...::.|.|.:|..:. :
 Worm    12 ILAYLATWIPTLLKYKR----HWQYGSKLPGPPAHPIFGNLGPIVGKKTEDLPSVFINWAAEQ-R 71

  Fly    69 DNFLFWIGYSSHIVM---------TNPKQLEYILNSQQLIQKSTIYDLLHPWLGHG-LLTSFGSK 123
            |.     |:|...||         .|.|....|::|.....|...|....||||.| ||..:|.:
 Worm    72 DQ-----GHSVMRVMILGKVYAWPLNGKAAAAIIDSTTETNKGDDYRFFDPWLGGGLLLEGYGER 131

  Fly   124 WHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMG 188
            |..||||:||:|||..|..:.||.|..|...:..|...||....:|...:.....||:|.:||||
 Worm   132 WKSHRKMLTPAFHFAKLGGYFEVFNNESKILIDLLSDFSASGETVDIFPYVKRCALDIISETAMG 196

  Fly   189 VPINAMEQRDSSIVQAFRDMCYN-IN-MRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQDFTYDII 251
            :.|:|....|...|||...  || |. :.:|:|..::..:|..|...:.|...|.||:..|..:|
 Worm   197 IKIDAQINHDHKYVQAVEG--YNKIGVLVSFNPHLKNQFIFWATGYKAQYDDYLSTLKSMTEKVI 259

  Fly   252 EKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDGRPLTRQEIYEEVSTFMFEGHDTTTSGV 316
            ::|..|..:|    :.:....::.|.|||.:||.. :...||.::|.:||.||||.|||||||..
 Worm   260 KERRAAHDSG----EVEKETSKRMMNFLDLMLSME-ESNQLTSEDIRQEVDTFMFAGHDTTTSST 319

  Fly   317 SFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYC 381
            |::.:.|:.:|:||.|:|:|..||.|.|.|..::.:.:..:.|||:.:||::|:...||.:.|..
 Worm   320 SWACWNLAHNPNVQEKVYKEMIEVFGDDPNTDITLENVNNLNYLDIVLKESKRIIAPVPALQRKL 384

  Fly   382 DKDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERF---EEEKPAPFEYLPFSAGPRNC 443
            ..|.:|:|.|||.|..:.::.::|..|..:||:|..|.|:||   |..|..|::::||.||||||
 Worm   385 TNDLEIDGYIVPAGGNVTISPMVLHSNHHVFKNPTEFNPDRFLPDEVSKRHPYDFMPFLAGPRNC 449

  Fly   444 IGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKYD---PIL 505
            ||||||.|..|.:||.:||:|::.|.:                             ||:   |.|
 Worm   450 IGQKFAQLNEKVMISHIVRNFKIEPTL-----------------------------KYNDTKPCL 485

  Fly   506 SAVLTLKSDNGLHLRLRER 524
            ..|  .|..||:.:||..|
 Worm   486 EVV--TKPSNGIPVRLIRR 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	160/468 (34%)
cyp-29A2	NP_505847.1	CYP4	75..497	CDD:410721	158/459 (34%)