Protein Alignment Cyp4e3 and cyp-13A10

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_496085.3
• Gene: cyp-13A10 / 174522
• WormBaseID: WBGene00014254
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 130/547 - (23%)
• Similarity: 227/547 - (41%)
• Gaps: 117/547 - (21%)

  Fly     8 LLVLPLITL----------VYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFDW 62
            ||.:|.:.:          .|:.|:.         ..||...|::|:..:..|:.........||
 Worm     5 LLAIPTLFIGFISYYLWIWTYWRRRG---------IPGPLGYPLVGSFPKTLKSEYPQYLQIRDW 60

  Fly    63 WYDYGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTI--YD-----LLHPWLGH------ 114
            ...||.     ..||:...:.|      .|::...::::..:  ||     .|:|..|.
 Worm    61 TKLYGP-----IYGYTEGTIKT------LIVSDIDIVRQIFVEQYDNFYGRKLNPIQGDPEKDER 114

  Fly   115 -GLLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLT 178
             .|.::.|.:|.:.|.:.:|:|..|.|:..:..:.:::.:.:..:::.::....||..:.....|
 Worm   115 TNLFSAQGFRWKRLRAISSPTFSNNSLRKINVTVEDSAMELLRHIEEQTSEGQQIDMLQFYQEFT 179

  Fly   179 LDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSN-----RVF-SLTPEFSAYQ 237
            :|.|...|||       |.||   |.|::..... :||.....|.:     .|| :|...|..:.
 Worm   180 MDTIGRIAMG-------QTDS---QMFKNPLLKF-VRAIFGDNRKHIPLIGGVFPTLAQVFRFFM 233

  Fly   238 KTLKTLQDFTYDIIEKRVY-ALQNGGSKEDHDPSLPRKK-------MAFLDTLLSSTID------ 288
            .....|....:..:.|.|. |:||...:.::|    ||.       ..|:|..|.:..|
 Worm   234 LKFPLLGAANFIHVNKTVVTAVQNRIDQREND----RKNGIEIGEPQDFIDLFLEARADDVEHFQ 294

  Fly   289 -------------GRPLTRQEIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYRE---Q 337
                         .|.||.|||..:...|:..|.|||...:|::.:||:.||:||:||..|   :
 Worm   295 ENNGDFSKTSSYGNRQLTTQEIVGQCLVFLIAGFDTTALSLSYTTFLLATHPEVQKKLQEEIERE 359

  Fly   338 CEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIG-----RYCDKDYDINGSIVPKGTT 397
            |      :..|:||..::|:||:|..|||..|:||    :|     |.|.:...:....|..||.
 Worm   360 C------IEPSISFDHLSKLKYMDCIIKETLRLYP----LGTMANSRRCMRATKLGNVEVEVGTM 414

  Fly   398 LNLALILLGYNDRIF-KDPHHFRPERF-EEEKPAPFE---YLPFSAGPRNCIGQKFALLELKTVI 457
            :.:....|..:.:|: .|...|:|||: :......|:   |:.|..|||.|:|.:.|.:|.|.::
 Worm   415 VQVDTWSLHTDTKIWGDDAKEFKPERWLDPNCDQVFQKGGYISFGLGPRQCVGMRLAYMEEKMLL 479

  Fly   458 SKVVR--SFEVLPAVDELVSTDGRLNT 482
            :.::|  :|||....:..:...||..|
 Worm   480 AHILRKYTFEVGTKTEIPLKLVGRATT 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	116/477 (24%)
cyp-13A10	NP_496085.3	CYP3A-like	64..509	CDD:410678	118/479 (25%)