Protein Alignment Cyp4e3 and cyp-44A1

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_495052.1
• Gene: cyp-44A1 / 173936
• WormBaseID: WBGene00000375
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 116/535 - (21%)
• Similarity: 217/535 - (40%)
• Gaps: 136/535 - (25%)

  Fly    32 EFNGPTPVPILGNANRIG------KNPAEILSTF----FDWWYDYG---KDNFLFWIGYSSHI-- 81
            |..||..:|::||   ||      |:.|:.:..:    .:.:..||   |:|..|...|..||
 Worm    32 EIPGPREIPVIGN---IGYFKYAVKSDAKTIENYNQHLEEMYKKYGKIVKENLGFGRKYVVHIFD 93

  Fly    82 ------VMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHKHRKMITPSFHFNIL 140
                  |:....:..:|:..|:..||......::|.||:    ..|.:|::.|..:.
 Worm    94 PADVQTVLAADGKTPFIVPLQETTQKYREMKGMNPGLGN----LNGPEWYRLRSSVQ-------- 146

  Fly   141 QDFHEVMNENSAKFMTQLKKASAGDTI------------IDFQEHANYLTLD----VICDTAMGV 189
               |.:|...|.:......:..:.|.:            :|.|:.|...:|:    ::.:.::|.
 Worm   147 ---HAMMRPQSVQTYLPFSQIVSNDLVCHVADQQKRFGLVDMQKVAGRWSLESAGQILFEKSLGS 208

  Fly   190 PINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSN------RVFSLTPEFSAYQKTLKTLQDFTY 248
            ..|..|..|..|         .:|.:.|....:..      |:|| ||.:    :.:..|:|..|
 Worm   209 LGNRSEWADGLI---------ELNKKIFQLSAKMRLGLPIFRLFS-TPSW----RKMVDLEDQFY 259

  Fly   249 DIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDT----LLSSTIDGRPLTRQEIYEEVSTFMFEGH 309
            ..:::.:            |.:|.:.|:...|:    ..|..|:.:.|.|:::...:.:...:|.
 Worm   260 SEVDRLM------------DDALDKLKVNDSDSKDMRFASYLINRKELNRRDVKVILLSMFSDGL 312

  Fly   310 DTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSV 374
            .||...:.:::|.|:.||:..:::.:|    :..|...|       |:.:|...|||..|::|..
 Worm   313 STTAPMLIYNLYNLATHPEALKEIQKE----IKEDPASS-------KLTFLRACIKETFRMFPIG 366

  Fly   375 PFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFKD-PHHFRPERFEEEKPA--PFEYLPF 436
            ..:.|...|:..::|..||.||.:::...:|..::.:|.| |..|:|:|:.|:...  ||.||||
 Worm   367 TEVSRVTQKNLILSGYEVPAGTAVDINTNVLMRHEVLFSDSPREFKPQRWLEKSKEVHPFAYLPF 431

  Fly   437 SAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKY 501
            ..|||.|.|::||..:|.|.::|:..::::                               ||:.
 Worm   432 GFGPRMCAGRRFAEQDLLTSLAKLCGNYDI-------------------------------RHRG 465

  Fly   502 DPILSAVLTLKSDNG 516
            |||.....||....|
 Worm   466 DPITQIYETLLLPRG 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	104/486 (21%)
cyp-44A1	NP_495052.1	CYP24A1-like	70..478	CDD:410677	105/490 (21%)