Protein Alignment Cyp4e3 and Cyp26a1

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_569092.2
• Gene: Cyp26a1 / 154985
• RGDID: 620161
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 425
• Identity: 102/425 - (24%)
• Similarity: 179/425 - (42%)
• Gaps: 81/425 - (19%)

  Fly    77 YSSHI-------VMTNPKQLEYILNSQQLIQKSTIYDLLHPW-------LGHGLLTSFGSKWHKH 127
            |.:|:       ||........:|...:|:.       :| |       ||.|.|::.....||.
  Rat    79 YKTHLFGRPTVRVMGADNVRRILLGEHRLVS-------VH-WPASVRTILGAGCLSNLHDSSHKQ 135

  Fly   128 R-KMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGV-- 189
            | |:|..:|:...||.:..|:.|..:..:.|.  .|.|:..:........|...:.....:|.
  Rat   136 RKKVIMQAFNREALQCYVPVIAEEVSGCLEQW--LSCGERGLLVYPEVKRLMFRIAMRILLGCEP 198

  Fly   190 -PINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPE--FSAYQKTLKTLQDFTYDII 251
             |....|. :..:|:||.:|..|:              |||..:  ||...:.:|. ::..:..|
  Rat   199 GPAGGGED-EQQLVEAFEEMTRNL--------------FSLPIDVPFSGLYRGVKA-RNLIHARI 247

  Fly   252 EKRVYA----LQ----NGGSKEDHDPSLPRKKMAFLDTLLSSTID-GRPLTRQEIYEEVSTFMFE 307
            |:.:.|    ||    :.|.|:            .|..|:..:.: |..|..|.:.:..:..:|.
  Rat   248 EENIRAKIRRLQAAEPDAGCKD------------ALQLLIEHSWERGERLDMQALKQSSTELLFG 300

  Fly   308 GHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMG-----HDMNRSVSFQEIAKMKYLDLFIKEA 367
            ||:||.|..:..:..|..:|.|.:|: ||:.:..|     |..:: :..:.:.::||:...|||.
  Rat   301 GHETTASAATSLITYLGLYPHVLQKV-REEIKSKGLLCKSHHEDK-LDMETLEQLKYIGCVIKET 363

  Fly   368 QRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYND--RIFKDPHHFRPERF---EEEK 427
            .|:.|.||...|...|.:::||..:|||  .|:...:...:|  ..|.:...|.|:||   ..|.
  Rat   364 LRLNPPVPGGFRVALKTFELNGYQIPKG--WNVIYSICDTHDVADSFTNKEEFNPDRFTSLHPED 426

  Fly   428 PAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVR 462
            .:.|.::||..|.|:|:|::||.:.||....::.|
  Rat   427 TSRFSFIPFGGGLRSCVGKEFAKILLKIFTVELAR 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	102/425 (24%)
Cyp26a1	NP_569092.2	cytochrome_P450	55..490	CDD:477761	102/425 (24%)