Protein Alignment Cyp4e3 and Cyp4a10

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 548
• Identity: 154/548 - (28%)
• Similarity: 268/548 - (48%)
• Gaps: 91/548 - (16%)

  Fly     4 AVLALLVLPLITLVYFERKASQRRQLLKEFNG-PTPVPILGNANRIGKNPAEILSTFFDWWYDYG 67
            :||.||:| |:..|.|   ...|:.|||.|.. |:|.                    |.|::.:.
Mouse    23 SVLGLLLL-LVKAVQF---YLHRQWLLKAFQQFPSPP--------------------FHWFFGHE 63

  Fly    68 K--------------DNF------LFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWL 112
            |              :||      .|| |..:::.:.:|..::.||.... .:.:..|.||.||:
Mouse    64 KFKGDQELQEIVSCIENFPSAFPRWFW-GSKAYLTVYDPDYMKVILGRSD-PKANGAYRLLAPWI 126

  Fly   113 GHGLLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYL 177
            |:|||...|..|.:||:|:||:||::||:.:.:.|.::....:.:.::.:..|:.|:..:|.:.:
Mouse   127 GYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQDSSIEIFQHISLM 191

  Fly   178 TLDVICDTAM----GVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQK 238
            |||.:...|.    .|.::...:   :.:||..|:....:.|..:.|.:::.::.|:......::
Mouse   192 TLDTVMKCAFSHKGSVQVDGNYR---TYLQAIGDLNNLFHSRVRNIFHQNDTIYKLSSNGRLAKQ 253

  Fly   239 TLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTID-GRPLTRQEIYEEVS 302
            ..:...|.|..:|:.|...||:.|..|   ....::::.|||.||.:.:: |..::.:::..||.
Mouse   254 ACQLAHDHTDGVIKLRKDQLQDEGELE---KIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVD 315

  Fly   303 TFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEA 367
            ||||||||||.||||:..|.|:.|||.|::...|...::|.  ..|:::..:.::.|..:.||||
Mouse   316 TFMFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLGD--GSSITWDHLDQIPYTTMCIKEA 378

  Fly   368 QRVYPSVPFIGRYCDKDYDI-NGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKPA-P 430
            .|:||.||.|.|........ :|..:|||..:.|::..|.:|.:::.:|..|.|.||..:.|. .
Mouse   379 LRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHS 443

  Fly   431 FEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKRE 495
            ..:||||.|.|||||::||:.|||.:::..:..||:||....:
Mouse   444 HSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRV---------------------- 486

  Fly   496 AGRHKYDPILSAVLTLKSDNGLHLRLRE 523
                   |:..|.|.|||.||::|.|::
Mouse   487 -------PMPLARLVLKSKNGIYLHLKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	135/477 (28%)
Cyp4a10	NP_034141.3	CYP4B-like	71..504	CDD:410771	134/471 (28%)