Protein Alignment Cyp4e3 and LOC1273546

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_001237478.4
• Gene: LOC1273546 / 1273546
• VectorBaseID: AGAMI1_006380
• Length: 494
• Species: Anopheles gambiae
• Alignment Length: 535
• Identity: 183/535 - (34%)
• Similarity: 281/535 - (52%)
• Gaps: 55/535 - (10%)

  Fly     1 MWLAVLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEI-LSTFFDWWY 64
            :::.::||.|| ::..|.|..|.   .:.:....||....:|||...:.:...:: ....|:::.
Mosquito     3 VYVLLIALCVL-VLRFVAFRYKV---YRTVGHLPGPPVNFLLGNTLELVRYDTQVFFEKLFEYFQ 63

  Fly    65 DYGKDNFL-----FWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKW 124
            .||....|     .||.:||      |..:|.|::|.:..:||..||:|..|||:|:|..:|:.|
Mosquito    64 RYGTIVRLDMINKVWIIFSS------PHDIEQIISSNEFNRKSMDYDILQEWLGNGILLDYGNTW 122

  Fly   125 HKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGV 189
            ..:|:.:|.:|||.||..:..|..|.:...:.:|  ..||...:|........|||||.:|:|||
Mosquito   123 FSNRRALTGAFHFKILDTYVPVFEEQADVLVRKL--LDAGGATVDIFAMVKLYTLDVILETSMGV 185

  Fly   190 PINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQDFTYDIIEKR 254
            ...| :..||..|:|..|:.:....|.::....|:..|.||..:..|:|:|:..::||..:|.:|
Mosquito   186 RCRA-QLEDSDYVRAVTDLTHITFWRMYNAMGFSDWTFRLTKHYQTYRKSLQINREFTTSVITQR 249

  Fly   255 VYALQNGGSKEDHDPSLPRK-KMAFLDTLLSSTIDGRPLTRQEIYEEVSTFMFEGHDTTTSGVSF 318
            ...|...|..   |.:.|.| :::.||.||.|.|.||..:.:|:|.:|:.|||.|||||:|.::|
Mosquito   250 RAELLAAGIS---DTTRPEKGRLSLLDILLRSDITGRTFSDEEVYSQVNNFMFAGHDTTSSAITF 311

  Fly   319 SVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYPSVPFIGRYCDK 383
            .:|..::||:||:::|.|  .|:.......|:.|.:..:|||:..|||:.|::|.||:..|:.|.
Mosquito   312 ILYACAKHPEVQQRVYEE--IVVELPDGEPVTQQRVNNLKYLEQVIKESLRMFPPVPYYSRHIDH 374

  Fly   384 DYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFE--EEKPAPFEYLPFSAGPRNCIGQ 446
            |....|..:.||:|:.|...:|.:|...|.:|..||||||.  |.|..||.|:|||||.||||||
Mosquito   375 DTTQGGVRLEKGSTIVLGTYMLHHNPEYFPEPDQFRPERFADGETKRNPFAYIPFSAGSRNCIGQ 439

  Fly   447 KFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRHKYDPILSAVLTL 511
            ||||.||||.:.|::|..:|     ||...|        ..|  |:|.|             |.|
Mosquito   440 KFALNELKTALVKILRQCKV-----ELPDPD--------FVP--KMKME-------------LVL 476

  Fly   512 KSDNGLHLRLRERRS 526
            |..||:.||..||::
Mosquito   477 KPVNGMQLRFLERKT 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	164/458 (36%)
LOC1273546	XP_001237478.4	None