Protein Alignment Cyp4e3 and Cyp4f15

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_598888.1
• Gene: Cyp4f15 / 106648
• MGIID: 2146921
• Length: 534
• Species: Mus musculus
• Alignment Length: 560
• Identity: 161/560 - (28%)
• Similarity: 260/560 - (46%)
• Gaps: 95/560 - (16%)

  Fly     2 WLAVLAL----LVLPLITLVYFERKASQRRQLLKEFNGPTPVP---ILGNANRIG------KNPA 53
            ||.:|.:    |:..::|..|...:....   |.:|  |.|..   .||:...|.      |...
Mouse    24 WLLLLLIGASWLLARVLTQTYIFYRTYHH---LCDF--PQPPKWNWFLGHLGMITPTEHGLKEVT 83

  Fly    54 EILSTFFDWWYDYGKDNFLFWIGYSSHIV-MTNPKQLEYILNSQQ--LIQKSTIYDLLHPWLGHG 115
            .:::|:        ...|:.|:|....|: :.:|..:..:||:..  .:::...|..|.||||.|
Mouse    84 NLVATY--------PQGFMTWLGPIIPIITLCHPDIIRSVLNASASVALKEVVFYSFLKPWLGDG 140

  Fly   116 LLTSFGSKWHKHRKMITPSFHFNILQDFHEVMNENS----AKFMTQLKKASAGDTIIDFQEHANY 176
            ||.|.|.||..||:|:||:||||||:.:.::.|:::    ||:.   ..||.|...:|..|:.:.
Mouse   141 LLLSDGDKWSSHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQ---HLASGGSARLDVFENISL 202

  Fly   177 LTLDVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLK 241
            :|||.:.........|..| ..|..:.|..::...:..|........:.::.||.....:.|...
Mouse   203 MTLDSLQKCVFSFDSNCQE-NPSEYISAILELSALVTKRYHQLLLHIDSLYQLTCSGRRFHKACH 266

  Fly   242 TLQDFTYDIIEKRVYALQNGGSKEDHD---PSLPRKKMAFLDT-LLSSTIDGRPLTRQEIYEEVS 302
            .:..||..:|:.|...|.   ||.:.|   .....|.:.|:|. |||...||:.|:.::|..|..
Mouse   267 LVHSFTDAVIQDRRRTLP---SKHEDDVLKAKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEAD 328

  Fly   303 TFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEI------------A 355
            ||||||||||.||:|:.:|.|:|||:     |:|:|.....::.|.....||            |
Mouse   329 TFMFEGHDTTASGLSWILYNLARHPE-----YQERCRQEVQELLRDRESTEIECSCAVFLRDDLA 388

  Fly   356 KMKYLDLFIKEAQRVYPSVPFIGRYCDKDYDI-NGSIVPKGTTLNLALILLGYNDRIFKDPHHFR 419
            ::.:|.:.|||:.|::|.|..|.|.|.:|..: :|.::|||....:.:....:|..::.||..:.
Mouse   389 QLPFLTMCIKESLRLHPPVTVISRRCTQDIVLPDGRVIPKGVICIINIFATHHNPTVWPDPEVYD 453

  Fly   420 PERFEEEK---PAPFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLN 481
            |.||:.|.   .:|..::||||||||||||.||:.|:|..::..:..|.||
Mouse   454 PFRFDPENIKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFRVL-------------- 504

  Fly   482 TYLGLAPDEKLKREAGRHKYDPILSAVLTLKSDNGLHLRL 521
                  ||:|          :|.....|.|:::.||.||:
Mouse   505 ------PDDK----------EPRRKPELILRAEGGLWLRV 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	144/477 (30%)
Cyp4f15	NP_598888.1	CYP4F	79..527	CDD:410772	146/497 (29%)