Protein Alignment Cyp4e3 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_598730.1
• Gene: Cyp4v3 / 102294
• MGIID: 2142763
• Length: 525
• Species: Mus musculus
• Alignment Length: 551
• Identity: 201/551 - (36%)
• Similarity: 289/551 - (52%)
• Gaps: 87/551 - (15%)

  Fly     4 AVLALLVLPLITLVYFERKASQRRQLLKEFNGPT---PVPILGNANRIGKNPAEILSTFFDWWYD 65
            |.:.:.:.|:  ||.:.||..|.|.:      |:   ..|::|:|..:..|.||    ||.....
Mouse    27 ATILISIFPM--LVSYARKWQQMRSI------PSVARAYPLVGHALYMKPNNAE----FFQQLIY 79

  Fly    66 YGKD-----NFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWH 125
            |.::     ....|||....:.:...:.:|.||.|.:.|.||.:|..|.||||.|||||.||||.
Mouse    80 YTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFLYKFLQPWLGLGLLTSTGSKWR 144

  Fly   126 KHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHAN--------YLT---L 179
            ..|||:||:|||.||::|.:||||.:...:.:|:|            |.|        |:|   |
Mouse   145 TRRKMLTPTFHFTILENFLDVMNEQANILVNKLEK------------HVNQEAFNCFFYITLCAL 197

  Fly   180 DVICDTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTLQ 244
            |:||:||||..|.|....||..|:....|...|..|...|:...:..:.:..|...:::.||.|.
Mouse   198 DIICETAMGKNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVFKEGRDHKRGLKCLH 262

  Fly   245 DFTYDIIEKRVYALQNGGSKEDHD-------PSLPRKKMAFLDTLLSST-IDGRPLTRQEIYEEV 301
            .||.::|.:||   :...::||..       || ..|:.||||.|||.| .:|..|::::|.|||
Mouse   263 TFTNNVIAERV---KERKAEEDWTGAGRGPIPS-KNKRKAFLDLLLSVTDEEGNRLSQEDIREEV 323

  Fly   302 STFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKE 366
            .||||||||||.:.:::|:|||..:|:||||:.:|..||.|.. :|.|:.:::.|:||||..|||
Mouse   324 DTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRS-HRPVTLEDLKKLKYLDCVIKE 387

  Fly   367 AQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEEEKPA-- 429
            ..||:||||...|...:|.::.|..|.|||...:....|..:.|.|.||..||||||..|...
Mouse   388 TLRVFPSVPLFARSLSEDCEVGGYKVTKGTEAIIIPYALHRDPRYFPDPEEFRPERFFPENSQGR 452

  Fly   430 -PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLK 493
             |:.|:|||||||||||||||::|.||:::.::|.|.|         ...:....||||.|
Mouse   453 HPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFWV---------ESNQKREELGLAGD---- 504

  Fly   494 REAGRHKYDPILSAVLTLKSDNGLHLRLRER 524
                           |.|:.:||:.::|:.|
Mouse   505 ---------------LILRPNNGIWIKLKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	181/477 (38%)
Cyp4v3	NP_598730.1	CYP4V	76..515	CDD:410773	182/483 (38%)