Protein Alignment Cyp4e3 and Cyp3a41b

DIOPT Version :9

• Sequence 1: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 542
• Identity: 134/542 - (24%)
• Similarity: 258/542 - (47%)
• Gaps: 101/542 - (18%)

  Fly    10 VLPLITLVYFERKASQRRQLLKE--FNGPTPVPILGNANRIGKNPAEILSTFFDWW------YD- 65
            ||..|.||...|..::...|.|:  ..||.|:|.||.          :|:.:...|      |:
Mouse    13 VLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGT----------VLNYYKGLWKFDMECYEK 67

  Fly    66 YGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLT-----SFGSKWH 125
            |||...|| .|.....|:|:|:.::.:|..:..    :::.....:...|:::     |...:|.
Mouse    68 YGKTWGLF-DGQMPLFVITDPEMIKNVLVKECF----SVFTNRREFGPVGIMSKAISISKDEEWK 127

  Fly   126 KHRKMITPSF-------HFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVIC 183
            ::|.:::|:|       .|.:::.:.:::    .|::.|  :|..|.. :..::.....::|||.
Mouse   128 RYRALLSPTFTSGKLKEMFPVIEQYGDIL----VKYLMQ--EAEKGKP-VTMKDVLGAYSIDVIT 185

  Fly   184 DTAMGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFS------LTPEFSAY------ 236
            .|:.||.::::...:...|:..:.:   :.:..|.|.     |||      |||.:...
Mouse   186 STSFGVNVDSLNNPEDPFVEKAKGI---LRVDFFDPL-----VFSVVLFPFLTPVYEMLNICMFP 242

  Fly   237 QKTLKTLQDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLLSSTIDG------RPLTRQ 295
            :.:::..:.|...:.|.|:      .||:.|       ::.||..::::..:.      :.|:..
Mouse   243 KDSIEFFKKFVNRMKESRL------DSKQKH-------RVDFLQLMMNAHNNSKDKDSHKALSDM 294

  Fly   296 EIYEEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYL 360
            ||..:...|:|.|::||:|.:||::|.|:.|||:|:||..|..|.:.:  ....::..:.:|:||
Mouse   295 EITAQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPN--KAPPTYDTVMEMEYL 357

  Fly   361 DLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERFEE 425
            |:.:.|..|:||....:.|:|.||.::||..:|||:|:.:....|.::.:.:.:|..|:||||.:
Mouse   358 DMVLNETLRLYPIGNRLERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSK 422

  Fly   426 EKPA---PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLA 487
            |...   |:.|:||..|||||||.:||.:.:|..::||:::|...|..:          |.:.|
Mouse   423 ENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQE----------TQIPL- 476

  Fly   488 PDEKLKREAGRHKYDPILSAVL 509
               ||.|:.......||:..|:
Mouse   477 ---KLSRQGLLQPEKPIVLKVV 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	117/472 (25%)
Cyp3a41b	NP_001098629.1	p450	39..494	CDD:278495	125/513 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810