Protein Alignment CG4364 and NOP7

DIOPT Version :9

• Sequence 1: NP_609305.1
• Gene: CG4364 / 34287
• FlyBaseID: FBgn0032138
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_011617.1
• Gene: NOP7 / 852995
• SGDID: S000003335
• Length: 605
• Species: Saccharomyces cerevisiae
• Alignment Length: 656
• Identity: 227/656 - (34%)
• Similarity: 351/656 - (53%)
• Gaps: 94/656 - (14%)

  Fly     1 MRRPKKYESGEATQYISRRAALRKLQLSLNDFRRLCILKGVYPREPKHRRRAQKGSSEIKVLYHT 65
            ||..||...|.|..:|:|..|:||||:||.|||||||.||:|||||:::::|.|||:.....|:.
Yeast     1 MRIKKKNTRGNARNFITRSQAVRKLQVSLADFRRLCIFKGIYPREPRNKKKANKGSTAPTTFYYA 65

  Fly    66 KDIRFLLHESIVWTLRDYKIFAKKSNRDRAIKDFRNLKRRLALFPEIKLDHIVKERYPTFIDALK 130
            |||::|:||.::...|::|.||:|..|.....:..:.||.........||||:|||||:|.||::
Yeast    66 KDIQYLMHEPVLAKFREHKTFARKLTRALGRGEVSSAKRLEENRDSYTLDHIIKERYPSFPDAIR 130

  Fly   131 DLDDCLTLLFLFSTFPSLHLIPREQSNLCRRLTIEFLHYVIASKSLRKVFISIKGYYFQAEIKGQ 195
            |:||.|.:|||||..||.:.:..:..|..:::..::|.||...:.:||||:||||.|:||.|||:
Yeast   131 DIDDALNMLFLFSNLPSTNQVSSKIINDAQKICNQWLAYVAKERLVRKVFVSIKGVYYQANIKGE 195

  Fly   196 KVTWIVPHYYPFKPQSRQEVDFKVMSIFVEFYTIMLGFTNFRLFHGLNLAYPPQFP--------- 251
            :|.|:||..:|....|  :|||::|..|:|||:.:|.|..::|:....|.|||:..
Yeast   196 EVRWLVPFKFPENIPS--DVDFRIMLTFLEFYSTLLHFVLYKLYTDSGLIYPPKLDLKKDKIISG 258

  Fly   252 -SSVLQDS--------------EESLKDEASFVSDRIAALNFELLRTD-------------KVQE 288
             ||.:.:|              ||.:|.|:...|...:|||.:...||             |.||
Yeast   259 LSSYILESRQEDSLLKLDPTEIEEDVKVESLDASTLKSALNADEANTDETEKEEEQEKKQEKEQE 323

  Fly   289 DEEELDIDMELLEQDGDSKRIIKMKQEAQEVSRLRTLFKGLKFFINREVPREPLVILIRSFGGKV 353
            .|:..:.:::..|.:..:|..| :.|.::..|.:.:||....|:::||||.:.|..||.|.||.|
Yeast   324 KEQNEETELDTFEDNNKNKGDI-LIQPSKYDSPVASLFSAFVFYVSREVPIDILEFLILSCGGNV 387

  Fly   354 SWDSSIFAGSTYDEGD-ETITHQIVDRPSITTQYISRDYIQPQWVFDCVNQRQLLPTNKYFIGET 417
            ..::::.......:.| ..:||||||||.:..:...|.||||||:|||:|:.:|:|.|||..||.
Yeast   388 ISEAAMDQIENKKDIDMSKVTHQIVDRPVLKNKVAGRTYIQPQWIFDCINKGELVPANKYLPGEA 452

  Fly   418 LPPHLSPFVDS-KRDSYIPPEEKALLDPSLIETHAQSDDDSEDEAQEEEETVDQELLDAQLQLAY 481
            |||||||:.|: ..|...|.||..       |..::|:.:|||:.:||    |||::..:
Yeast   453 LPPHLSPWGDAIGYDPTAPVEEGE-------EEESESESESEDQVEEE----DQEVVAGE----- 501

  Fly   482 QQETAEYKKYGGPDGVNEDEEDPDDEDDNEDDDEEEEELDEKTKRLQEEKQKMSVQSGKVHKVNK 546
                                         ||||::||...:|...|:.:..|.|..|.....|||
Yeast   502 -----------------------------EDDDDDEELQAQKELELEAQGIKYSETSEADKDVNK 537

  Fly   547 RQVHKAEVDEH----RLQARMVKPRHRNLFRKLIREKQTKEKEEWLLRKKRRTIEANEKEARKTA 607
            .:..|.:|||.    :|:..|:..:.:.|::|:......||::...|:||::.|   .|:..|..
Yeast   538 SKNKKRKVDEEEEEKKLKMIMMSNKQKKLYKKMKYSNAKKEEQAENLKKKKKQI---AKQKAKLN 599

  Fly   608 KREARK 613
            |.:::|
Yeast   600 KLDSKK 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4364	NP_609305.1	NOP7	1..601	CDD:227492	223/642 (35%)
		Pescadillo_N	7..268	CDD:284208	113/284 (40%)
		BRCT_2	323..413	CDD:293197	38/90 (42%)
NOP7	NP_011617.1	NOP7	1..605	CDD:227492	226/654 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346009
Domainoid	1	1.000	221	1.000	Domainoid score	I452
eggNOG	1	0.900	-	-		E1_COG5163
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5984
Inparanoid	1	1.050	352	1.000	Inparanoid score	I392
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53633
OrthoFinder	1	1.000	-	-		FOG0004447
OrthoInspector	1	1.000	-	-		oto99387
orthoMCL	1	0.900	-	-		OOG6_102136
Panther	1	1.100	-	-	LDO	PTHR12221
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R899
SonicParanoid	1	1.000	-	-		X3152
TreeFam	1	0.960	-	-
	15	14.790