DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4364 and AT5G14520

DIOPT Version :9

Sequence 1:	NP_609305.1	Gene:	CG4364 / 34287	FlyBaseID:	FBgn0032138	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_196956.1	Gene:	AT5G14520 / 831303	AraportID:	AT5G14520	Length:	590	Species:	Arabidopsis thaliana

Alignment Length:	645	Identity:	230/645 - (35%)
Similarity:	337/645 - (52%)	Gaps:	102/645 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PKKY------ESGEATQYISRRAALRKLQLSLNDFRRLCILKGVYPREPKHRRRAQKGSSEIKVL 62
            ||.|      :.|.|.:|::|..||:.||::||.||||||:||::|||||   :..||:..  ..
plant     2 PKHYRPTGKKKEGNAARYMTRSQALKHLQVNLNLFRRLCIVKGIFPREPK---KKIKGNHH--TY 61

  Fly    63 YHTKDIRFLLHESIVWTLRDYKIFAKKSNRDRAIKDFRNLKRRLALFPEIKLDHIVKERYPTFID 127
            ||.|||.||:||.::...|:.|.:.||..:.:|.|:....:..|...|..|||.:::||||||||
plant    62 YHVKDIAFLMHEPLLEKFREIKTYQKKVKKAKAKKNEELARLLLTRQPTYKLDRLIRERYPTFID 126

  Fly   128 ALKDLDDCLTLLFLFSTFPSLHLIPREQSNL-------CRRLTIEFLHYVIASKSLRKVFISIKG 185
            ||:|||||||::.||:..|:     .::.||       |||||.|:..|:..|.:|||||:|:||
plant   127 ALRDLDDCLTMVHLFAVLPA-----SDRENLEVKRVHNCRRLTHEWQAYISRSHALRKVFVSVKG 186

  Fly   186 YYFQAEIKGQKVTWIVPHYYPFKPQSRQEVDFKVMSIFVEFYTIMLGFTNFRLFHGLNLAYPPQF 250
            .|:||||:|||:||:.||  ..:.....:|||.|:..|:|||..:|.|.||:|:|.||:.|||
plant   187 IYYQAEIEGQKITWLTPH--AIQQVFTNDVDFGVLLTFLEFYETLLAFINFKLYHSLNVKYPP-- 247

  Fly   251 PSSVLQDSEESLKDEASFVSDRIAALNFELLRTDKV-------QEDEEELDIDMELLE------Q 302
               :|....|:|..:...:|..|.|.:..:....||       ..|.||.::.:..|:      :
plant   248 ---ILDSRLEALAADLYALSRYIDASSRGMAVEPKVDASFSSQSNDREESELRLAQLQHQLPSSE 309

  Fly   303 DGDSKRII----KMKQEAQEVSRLRTLFKGLKFFINREVPREPLVILIRSFGGKVSWDSSIFAGS 363
            .|....::    |..:|.:|....::|||.||||::||||||.|.::|.:|||.|||:..   |:
plant   310 PGALMHLVADNNKEVEEDEETRVCKSLFKDLKFFLSREVPRESLQLVITAFGGMVSWEGE---GA 371

  Fly   364 TYDEGDETITHQIVDRPSITTQYISRDYIQPQWVFDCVNQRQLLPTNKYFIGETLPPHLSPFVDS 428
            .:.|.||:|||.|:|:||....|:||.|:||||::||||.|.:|||.||.:|...|||||||||:
plant   372 PFKEDDESITHHIIDKPSAGHLYLSRVYVQPQWIYDCVNARIILPTEKYLVGRIPPPHLSPFVDN 436

  Fly   429 KRDSYIPPEEKALLDPSLIETHAQSDDDSEDEAQEEEETVDQELLDAQLQLAYQQETAEYKKYGG 493
            :.:.|:|                           :..||:      .:||.|.:.|.......|
plant   437 EAEGYVP---------------------------DYAETI------KRLQAAARNEVLPLPGVG- 467

  Fly   494 PDGVNEDEEDPDD--EDDNEDDDEEEEELDEKTKRLQEEKQ-----KMSVQSGKVHKVNKRQVHK 551
                .||.|||.:  ........||.|....|.|...:|||     ||.:...|  .|....:.:
plant   468 ----KEDLEDPQNLLYAGVMSRAEEAEAAKNKKKMAAQEKQYHEELKMEINGSK--DVVAPVLAE 526

  Fly   552 AEVDEHRLQARMVKPRHRNLFRKLIREKQTKEKEEWLLRKKRR-----TIEANEKEARKT 606
            .|.:|....|..:.....::.:.|:..|:.|..:...:.:.|:     .||..:|....|
plant   527 GEGEESVPDAMQIAQEDADMPKVLMSRKKRKLYDAMKISQSRKRSGVEIIEQRKKRLNDT 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4364	NP_609305.1	NOP7	1..601	CDD:227492	228/638 (36%)
		Pescadillo_N	7..268	CDD:284208	118/273 (43%)
		BRCT_2	323..413	CDD:293197	49/89 (55%)
AT5G14520	NP_196956.1	NOP7	6..583	CDD:227492	226/636 (36%)
AT5G14520	NP_196956.1	Pescadillo_N	11..264	CDD:399601	117/269 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	222	1.000	Domainoid score	I710
eggNOG	1	0.900	-	-		E1_COG5163
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5984
Inparanoid	1	1.050	354	1.000	Inparanoid score	I605
OMA	1	1.010	-	-		QHG53633
OrthoDB	1	1.010	-	-		D777920at2759
OrthoFinder	1	1.000	-	-		FOG0004447
OrthoInspector	1	1.000	-	-		oto3979
orthoMCL	1	0.900	-	-		OOG6_102136
Panther	1	1.100	-	-	LDO	PTHR12221
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3152
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840