Protein Alignment CG4364 and pes

DIOPT Version :9

• Sequence 1: NP_609305.1
• Gene: CG4364 / 34287
• FlyBaseID: FBgn0032138
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_571105.3
• Gene: pes / 30228
• ZFINID: ZDB-GENE-990415-206
• Length: 583
• Species: Danio rerio
• Alignment Length: 628
• Identity: 276/628 - (43%)
• Similarity: 381/628 - (60%)
• Gaps: 62/628 - (9%)

  Fly     5 KKYESGEATQYISRRAALRKLQLSLNDFRRLCILKGVYPREPKHRRRAQKGSSEIKVLYHTKDIR 69
            ||||||.||.||:|..|.:||.|||.||||||||||:||.||||:::..|||:..:..|..||||
Zfish     7 KKYESGSATNYITRNKARKKLSLSLADFRRLCILKGIYPHEPKHKKKVNKGSTAARTYYLLKDIR 71

  Fly    70 FLLHESIVWTLRDYKIFAKKSNRDRAIKDFRNLKRRLALFPEIKLDHIVKERYPTFIDALKDLDD 134
            |||||.||...|:||||.:|..:.....::..::|.....|..|||||:|||||||||||:|:||
Zfish    72 FLLHEPIVGKFREYKIFVRKLRKAYGKAEWSAVERLKENKPGYKLDHIIKERYPTFIDALRDVDD 136

  Fly   135 CLTLLFLFSTFPSLHLIPREQSNLCRRLTIEFLHYVIASKSLRKVFISIKGYYFQAEIKGQKVTW 199
            .|::.||||||........:...|||||::|:::|:|:|:||||||:||||.|:|||:.||.:||
Zfish   137 ALSMCFLFSTFARTGKCHVQTIQLCRRLSVEWMNYIISSRSLRKVFLSIKGIYYQAEVLGQTITW 201

  Fly   200 IVPHYYPFKPQSRQEVDFKVMSIFVEFYTIMLGFTNFRLFHGLNLAYPPQFPS----SVLQDSEE 260
            |||  |.|......:||::||:.|.|.||.:|||.||||:..|||.|||:...    |:..:.||
Zfish   202 IVP--YQFAHNHPTDVDYRVMATFTELYTTLLGFVNFRLYQTLNLVYPPKLDGQGEISLKAEFEE 264

  Fly   261 SLKDEASFVSDRIAALNFELLRTDKVQEDEEELDIDMELLEQDGDSKRIIKMKQEAQEVSRLRTL 325
            ....|:...:::::||:..|.|. ....:|||.::|....|.:...|..::.|.|.|: |:.:.|
Zfish   265 DYALESESYTEKLSALSASLARM-VASVEEEEAELDHFPTEGEDQEKMEVREKMEQQQ-SKQKKL 327

  Fly   326 FKGLKFFINREVPREPLVILIRSFGGKVSWDSSIFAGSTYDEGDETITHQIVDRPSITTQYISRD 390
            |:|||||:|||||||.|..:||.|||:||||.|:..||||:..||||||.||||||:..|||:|.
Zfish   328 FEGLKFFLNREVPRESLAFVIRCFGGEVSWDKSLCIGSTYEATDETITHHIVDRPSMDKQYINRY 392

  Fly   391 YIQPQWVFDCVNQRQLLPTNKYFIGETLPPHLSPFVDSKRDSYIPPEEKALLDPSLIETHAQSDD 455
            |||||||:|.||.:..||..:||:|.||||||||||:.....|:|||:..|:.....| ..|:::
Zfish   393 YIQPQWVYDSVNAKIQLPVEEYFLGVTLPPHLSPFVEETEGDYVPPEKLKLMALQRGE-KPQAEE 456

  Fly   456 DSEDEAQEEEETVDQELLDAQLQLAYQQETAEYKKYGGPDGVNEDEEDPDDEDDNEDDDEEEEE- 519
            |.|:|.:|||                                 :||||.:|::.:||::|.|||
Zfish   457 DEEEEGEEEE---------------------------------DDEEDEEDDEQSEDEEEAEEEA 488

  Fly   520 --LDEKTKRLQEEKQKMSVQSGKVHKVNK-RQVHKAEVDEHRLQARMVKPRHRNLFRKLIREKQT 581
              .:.:.||.|.:...:.|..||....|: |...:.:.:|.||...|:|.:.:.|:.|:
Zfish   489 NLAEMEEKRSQGKSLSVKVTPGKAKAENRARAAEEEKAEEKRLAIMMMKKKEKYLYDKI------ 547

  Fly   582 KEKEEWLLRKKRRTIEANEKEARKTAKREARKEAAAAAAKASK 624
                  :..|||:..|||    :..|||:|..:|:.|..|..|
Zfish   548 ------MFGKKRKVREAN----KLAAKRKAHDDASKADKKKKK 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4364	NP_609305.1	NOP7	1..601	CDD:227492	268/603 (44%)
		Pescadillo_N	7..268	CDD:284208	137/264 (52%)
		BRCT_2	323..413	CDD:293197	57/89 (64%)
pes	NP_571105.3	NOP7	6..566	CDD:227492	270/612 (44%)
		Pescadillo_N	9..279	CDD:284208	137/271 (51%)
		BRCT_2	329..415	CDD:293197	55/85 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	448..526		27/111 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	558..583		10/27 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594613
Domainoid	1	1.000	276	1.000	Domainoid score	I1713
eggNOG	1	0.900	-	-		E1_COG5163
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5984
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53633
OrthoDB	1	1.010	-	-		D245482at33208
OrthoFinder	1	1.000	-	-		FOG0004447
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102136
Panther	1	1.100	-	-	LDO	PTHR12221
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R899
SonicParanoid	1	1.000	-	-		X3152
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.750