DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pelo and Pelo

DIOPT Version :9

Sequence 1:	NP_476982.1	Gene:	pelo / 34286	FlyBaseID:	FBgn0011207	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_001007635.1	Gene:	Pelo / 294754	RGDID:	1359591	Length:	385	Species:	Rattus norvegicus

Alignment Length:	385	Identity:	257/385 - (66%)
Similarity:	322/385 - (83%)	Gaps:	2/385 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLLGKYVDKGMQGNVTLVPEESEDMWHAYNLIAKGDSVRSTTIRKVQNETATGSSTSSRVRTTL 65
            |||:.|.::|...|.|||||||.|||||.|||:..|||:|::||||||.|::|||..|:||||||
  Rat     1 MKLVRKDIEKDNAGQVTLVPEEPEDMWHTYNLVQVGDSLRASTIRKVQTESSTGSVGSNRVRTTL 65

  Fly    66 TIAVESIDFDTQACVLRLKGRNIEENQYVKMGAYHTLDLELNRKFELRKPEWDTIALERIEMACD 130
            |:.||:||||:|||.||:||.||:||:|||||||||::||.||:|.|.|.:||::.|||||.|||
  Rat    66 TLCVEAIDFDSQACQLRVKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACD 130

  Fly   131 PTQSADVAAVVMQEGLAHVCLITASMTLVRSKIEVSIPRKRKGSVQQHEKGLAKFYEQVMQSILR 195
            |..||||||||||||||||||:|.||||.|:|:||:|||||||:..||::.|.:|||||:|:|.|
  Rat   131 PAWSADVAAVVMQEGLAHVCLVTPSMTLTRAKVEVNIPRKRKGNCSQHDRALERFYEQVVQAIQR 195

  Fly   196 HVNFDVVKCVLIASPGFVRDQFYDYMFQQAVKMDYKLLLDNKSKFMLVHASSGFKHSLREILQDP 260
            |:||:||||:|:|||||||:||.|||||||||.|.|:||:|:|||:.||||||.|:||:|:|.||
  Rat   196 HINFEVVKCILVASPGFVREQFCDYMFQQAVKTDNKVLLENRSKFLQVHASSGHKYSLKEVLCDP 260

  Fly   261 AVLAKMSDTKAAGEVKALEQFYMMLQCEPAKAFYGKKHVLQAAESQAIETLLISDNLFRCQDVSL 325
            .|.:::||||||||||||:.||.|||.||.:||||.|.|.:|.|:.||:||||||.|||.|||:.
  Rat   261 TVASRLSDTKAAGEVKALDDFYKMLQHEPDRAFYGLKQVERANEALAIDTLLISDELFRHQDVAT 325

  Fly   326 RKEYVNLVESIRDAGGEVKIFSSMHISGEQLAQLTGIAALLRFPMPELEDSDDD--DDED 383
            |..||.||:|:::..|.|:||||:|:|||||.||||:||:||||:|||.|.:||  .:||
  Rat   326 RSRYVRLVDSVKENAGTVRIFSSLHVSGEQLGQLTGVAAILRFPVPELSDQEDDSSSEED 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pelo	NP_476982.1	PelA	1..371	CDD:224454	249/369 (67%)
		eRF1_1	1..128	CDD:281462	83/126 (66%)
		eRF1_2	136..268	CDD:281463	91/131 (69%)
		eRF1_3	271..370	CDD:281464	64/98 (65%)
Pelo	NP_001007635.1	PelA	1..371	CDD:224454	249/369 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354303
Domainoid	1	1.000	196	1.000	Domainoid score	I3036
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6835
Inparanoid	1	1.050	529	1.000	Inparanoid score	I1180
OMA	1	1.010	-	-		QHG62163
OrthoDB	1	1.010	-	-		D296113at33208
OrthoFinder	1	1.000	-	-		FOG0003168
OrthoInspector	1	1.000	-	-		oto98163
orthoMCL	1	0.900	-	-		OOG6_101450
Panther	1	1.100	-	-	LDO	PTHR10853
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2563
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.910