DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pelo and SPCC18B5.06

DIOPT Version :9

Sequence 1:	NP_476982.1	Gene:	pelo / 34286	FlyBaseID:	FBgn0011207	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_587936.1	Gene:	SPCC18B5.06 / 2539371	PomBaseID:	SPCC18B5.06	Length:	390	Species:	Schizosaccharomyces pombe

Alignment Length:	383	Identity:	191/383 - (49%)
Similarity:	280/383 - (73%)	Gaps:	0/383 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLLGKYVDKGMQGNVTLVPEESEDMWHAYNLIAKGDSVRSTTIRKVQNETATGSSTSSRVRTTL 65
            |||:.|.::|...|.:|:.|||.|||||.||::..||.::::|:|:|....||||::.|||...|
pombe     1 MKLIQKNIEKNGSGWITMCPEEPEDMWHLYNILQVGDQLKASTVRRVVKVGATGSTSGSRVVMKL 65

  Fly    66 TIAVESIDFDTQACVLRLKGRNIEENQYVKMGAYHTLDLELNRKFELRKPEWDTIALERIEMACD 130
            .|.||::||||:|..|.:|||..|.:..||||:||||||||:|.|.|.|.|||..||:|::.||:
pombe    66 RILVENMDFDTKAAQLHIKGRTTEYHPEVKMGSYHTLDLELHRNFTLYKNEWDAFALDRVDAACN 130

  Fly   131 PTQSADVAAVVMQEGLAHVCLITASMTLVRSKIEVSIPRKRKGSVQQHEKGLAKFYEQVMQSILR 195
            |:::|::.|||:.||||::||||..||::|.:|:..|||||:|....::|||.|||:.|.|||..
pombe   131 PSRNAEIGAVVLDEGLANICLITDYMTILRQRIDQVIPRKRRGDSSAYQKGLDKFYDSVFQSINS 195

  Fly   196 HVNFDVVKCVLIASPGFVRDQFYDYMFQQAVKMDYKLLLDNKSKFMLVHASSGFKHSLREILQDP 260
            ..:||.:|.|::||||||....|||:|..|||:|.|.::.:|:||:::|:|:|..|||.|||:||
pombe   196 EFDFDKLKVVILASPGFVARGLYDYIFSMAVKLDLKQIVKSKNKFVILHSSTGHIHSLNEILKDP 260

  Fly   261 AVLAKMSDTKAAGEVKALEQFYMMLQCEPAKAFYGKKHVLQAAESQAIETLLISDNLFRCQDVSL 325
            ||.:|::|||...|::.|.:||.::..:..||:||..|||:|.|..||..|||||:|||..|::.
pombe   261 AVESKLADTKYVQEIRVLNKFYDVMNEDDRKAWYGPNHVLKAFELGAIGELLISDSLFRSSDIAT 325

  Fly   326 RKEYVNLVESIRDAGGEVKIFSSMHISGEQLAQLTGIAALLRFPMPELEDSDDDDDED 383
            ||::|:|||.:::....|.||||:|.||:||..|:||||:|.:|:.|.:.|:|::||:
pombe   326 RKKWVSLVEGVKEINCPVYIFSSLHESGKQLDLLSGIAAILTYPVDEEDISEDEEDEE 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pelo	NP_476982.1	PelA	1..371	CDD:224454	186/369 (50%)
		eRF1_1	1..128	CDD:281462	65/126 (52%)
		eRF1_2	136..268	CDD:281463	67/131 (51%)
		eRF1_3	271..370	CDD:281464	46/98 (47%)
SPCC18B5.06	NP_587936.1	PelA	1..370	CDD:224454	185/368 (50%)
		eRF1_1	1..128	CDD:281462	65/126 (52%)
		eRF1_2	136..268	CDD:281463	67/131 (51%)
		eRF1_3	271..370	CDD:281464	46/98 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	142	1.000	Domainoid score	I1193
eggNOG	1	0.900	-	-		E1_COG1537
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6835
Inparanoid	1	1.050	390	1.000	Inparanoid score	I403
OMA	1	1.010	-	-		QHG62163
OrthoFinder	1	1.000	-	-		FOG0003168
OrthoInspector	1	1.000	-	-		oto101811
orthoMCL	1	0.900	-	-		OOG6_101450
Panther	1	1.100	-	-	LDO	PTHR10853
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R330
SonicParanoid	1	1.000	-	-		X2563
TreeFam	1	0.960	-	-
	14	13.860