Protein Alignment Pka-C1 and YPK2

DIOPT Version :10

• Sequence 1: NP_476977.1
• Gene: Pka-C1 / 34284
• FlyBaseID: FBgn0000273
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_013822.1
• Gene: YPK2 / 855130
• SGDID: S000004710
• Length: 677
• Species: Saccharomyces cerevisiae
• Alignment Length: 334
• Identity: 138/334 - (41%)
• Similarity: 202/334 - (60%)
• Gaps: 13/334 - (3%)

  Fly     9 NKKVDAAETVKEF------LEQ--AKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQH 65
            |.|:|:|..::.:      ||:  .|......::.:.....::|||:.:|.:|.||||:||.|:.
Yeast   299 NLKIDSAAQIRLYNHHWISLERGYGKLNITVDYKPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRK 363

  Fly    66 KPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGE 130
            |.|:..||:|.|.|..:|...:|.|||.|:.:|..:..||:|.|::.|:....||:||.::.|||
Yeast   364 KDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGE 428

  Fly   131 MFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAK--- 192
            :|.||:..||||...||||.|:::.|.:.||.||:|||||||||:|:|.||::.:.|||..|
Yeast   429 LFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNM 493

  Fly   193 RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGK 257
            :...:|.|.|||||||||||:|.:||.|.||||.||:|:|||..|.||::.:....:|:||:...
Yeast   494 KDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQP 558

  Fly   258 VRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCK 322
            :.||..|....||||..||..|.::|.|  ..|.::|:|..:|....|..:..|....|:.|..|
Yeast   559 LLFPDGFDPAAKDLLIGLLSRDPSRRLG--VNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVK 621

  Fly   323 GPGDTSNFD 331
            ...||:|||
Yeast   622 SEIDTANFD 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	131/291 (45%)
YPK2	NP_013822.1	YPK1_N_like	114..339	CDD:212165	7/39 (18%)
		Protein Kinases, catalytic domain	349..660	CDD:473864	127/284 (45%)