Protein Alignment Pka-C1 and PRKACB

DIOPT Version :9

• Sequence 1: NP_476977.1
• Gene: Pka-C1 / 34284
• FlyBaseID: FBgn0000273
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_891993.1
• Gene: PRKACB / 5567
• HGNCID: 9381
• Length: 398
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 284/338 - (84%)
• Similarity: 311/338 - (92%)
• Gaps: 2/338 - (0%)

  Fly    17 TVKEFLEQAKEEFEDKWRRNPT-NTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQ 80
            ::||||.:|||:|..|| .||| |.|.|:||||.||||||||||||:|:||.|:.||||||||||
Human    62 SMKEFLAKAKEDFLKKW-ENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQ 125

  Fly    81 KVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPH 145
            |||||||:||||||||||||:.|||||.|.|.||||||||||:|||||||||||||::|||||||
Human   126 KVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPH 190

  Fly   146 SRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAP 210
            :|||||||||.|||||.||||||||||||||||.|||::||||||||||||||||||||||||||
Human   191 ARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAP 255

  Fly   211 EIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNL 275
            ||||||||||||||||||||:|||||||||||||||||||||||||||||||||.||||||||||
Human   256 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNL 320

  Fly   276 LQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRI 340
            ||||||||:||||.||:|||..||||:||||||:|:|:||||||:.:|.||||||||||||.:|:
Human   321 LQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRV 385

  Fly   341 SSTEKCAKEFAEF 353
            |.||||||||.||
Human   386 SITEKCAKEFGEF 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	251/288 (87%)
PRKACB	NP_891993.1	STKc_PKA	89..378	CDD:271111	251/288 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	479	1.000	Domainoid score	I421
eggNOG	1	0.900	-	-		E1_KOG0616
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H121718
Inparanoid	1	1.050	605	1.000	Inparanoid score	I939
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	1	1.000	-	-		FOG0000539
OrthoInspector	1	1.000	-	-		otm41919
orthoMCL	1	0.900	-	-		OOG6_100326
Panther	1	1.100	-	-	O	PTHR24353
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R632
SonicParanoid	1	1.000	-	-		X747
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.860