DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-C1 and LOC556339

DIOPT Version :9

Sequence 1:	NP_476977.1	Gene:	Pka-C1 / 34284	FlyBaseID:	FBgn0000273	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	XP_021328301.1	Gene:	LOC556339 / 556339	-ID:	-	Length:	771	Species:	Danio rerio

Alignment Length:	360	Identity:	138/360 - (38%)
Similarity:	213/360 - (59%)	Gaps:	32/360 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NKKVDAAETVKEFLEQAKEE--FEDK----------WRRNP---------------TNTAALDDF 46
            |:.|...|.::.:|.:..||  ..|:          :.|:|               ::|:.|.:.
Zfish   397 NEMVGTYEELQAYLREYVEELSLSDERRNAVPQSPLYERSPEAAELRRLKEKATALSSTSFLKEL 461

  Fly    47 ERIKTLGTGSFGRVMIVQHKPTKD-YYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLR 110
            :.:.|||.|.||||.:|:.|.::| .:|:|.:.|:.:|..:|.||..:||.|||.....|:|.|.
Zfish   462 QVVATLGMGGFGRVELVKLKDSEDTAFALKCIKKKHIVDTRQQEHIYSEKIILQQTNSNFIVRLF 526

  Fly   111 YHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENL 175
            ..|:|:..:||:||...|||::|.||.:..|.||.:||....::.||:|||...::|||||||||
Zfish   527 RTFRDDKFVYMLLEVCLGGELWSLLRDMSCFDEPTARFCTGCVLEAFDYLHGKGIVYRDLKPENL 591

  Fly   176 LIDSQGYLKVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGY 238
            |:|::||:|:.||||||::  ..:|||.||||||:|||:|::||::...|.|:||:|::|:..|.
Zfish   592 LLDAEGYVKMADFGFAKKIGLGKKTWTFCGTPEYVAPEVIMNKGHDFGADCWSLGILIFELLIGS 656

  Fly   239 PPFFADQPIQIYEKIVSG--KVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFA 301
            |||....||:||..::.|  ||..|.......:||:|.|.:::..:|.||.|.|:.|||..|||.
Zfish   657 PPFTGSDPIRIYTMVLHGIEKVDIPKRISKRPEDLIRRLCKLNPAERLGNKKNGIIDIKKHKWFQ 721

  Fly   302 STDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEE 336
            ..:|..:.::|:.:|.....|||.|.|.||.:..|
Zfish   722 GFNWEGLRRRKLMSPLRRELKGPLDHSYFDMFPPE 756

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	126/293 (43%)
LOC556339	XP_021328301.1	CAP_ED	177..286	CDD:237999
		CAP_ED	295..410	CDD:237999	3/12 (25%)
		STKc_cGK	467..727	CDD:270724	116/259 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910